51560-21-5

Usage

Uses

Used in Organic Synthesis:
1,4-DIIODO-2,5-DIMETHOXYBENZENE is used as a key intermediate in the synthesis of various organic compounds due to its reactive iodine atoms and methoxy groups, which can be further functionalized in chemical reactions.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 1,4-DIIODO-2,5-DIMETHOXYBENZENE is used as a starting material or building block for the development of new drugs. Its unique structure allows for the creation of molecules with specific therapeutic properties.
Used in Agrochemical Development:
Similarly, in agrochemicals, 1,4-DIIODO-2,5-DIMETHOXYBENZENE serves as a precursor in the synthesis of compounds with pesticidal or herbicidal activity, contributing to the development of more effective crop protection agents.
Used in Fine Chemicals Manufacturing:
1,4-DIIODO-2,5-DIMETHOXYBENZENE is also utilized in the production of fine chemicals, which are high-purity chemicals used in various applications such as fragrances, dyes, and other specialty chemicals.
Safety Considerations:
It is important to handle 1,4-DIIODO-2,5-DIMETHOXYBENZENE with care, as iodine-containing chemicals can pose toxicity and hazards if not used or stored properly, necessitating appropriate safety measures during its use in chemical processes.

InChI:InChI=1/C8H8I2O2/c1-11-7-3-6(10)8(12-2)4-5(7)9/h3-4H,1-2H3

Upstream product

• 102-56-7 2,5-dimethoxyaniline 
• 91-16-7 1,2-dimethoxybenzene 
• 150-78-7 1,4-dimethoxybezene 
• 186134-37-2 3-iodo-4-methoxyphenyl 4-methylbenzenesulfonate 
• 98279-45-9 3-iodo-4-methoxyphenol 
• 3899-91-0 4-methoxyphenyl p-toluenesulfonate 
• 25245-35-6 1-iodo-2,4-dimethoxybenzene 

Downstream Products

• 6301-35-5 1-iodo-2,5-dimethoxy-4-nitro-benzene 
• 78889-43-7 2,5-bis(3'-N-morpholino-1'-propynyl)-1,4-dimethoxybenzene 
• 78889-37-9 ((2,5-dimethoxy-1,4-phenylene)bis(ethyne-2,1-diyl))dibenzene 
• 78889-39-1 2,5-bis(3'-hydroxy-3'-methyl-1'-butynyl)-1,4-dimethoxybenzene 
• 7310-97-6 2,5-dimethoxyterephthalaldehyde 
• 90064-47-4 4-iodo-2,5-dimethoxybenzenecarbaldehyde 
• 78889-38-0 2,5-di-(p-anisylethynyl)-1,4-dimethoxybenzene 
• 203579-53-7 2,5-diiodo-1,4-benzoquinone 
• 294674-95-6 1,4-bis(tri-methylsilylethynyl)-2,5-bis(methoxyl)benzene 
• 791068-98-9 C₂₆H₁₈O₆ 
• 842120-12-1 1-hydroxy-2,5-diiodo-4-methoxybenzene 
• 138809-37-7 N,N'-dicyano-2,5-diiodo-1,4-benzoquinonediimine 
• 203579-62-8 2,5-bis(trifluoromethyl)-1,4-benzoquinone 
• 203579-41-3 2,5-bis(trifluoromethyl)-1,4-hydroquinone 

Relevant academic research and scientific papers

Practical electrochemical iodination of aromatic compounds

A practical method for electrochemical iodination of aromatic compounds was developed. The method involves the generation of I+ by electrochemical oxidation of I2 in CH3CN using H 2SO4 as supporting electrolyte followed by the reaction with aromatic compounds. The para/ortho selectivity for the reaction of mono-substituted benzenes was significantly improved using dimethoxyethane as cosolvent in the second step. The reaction with highly reactive aromatic compounds led to the formation of significant amounts of diiodo compounds in a macrobatch reactor. This problem was solved by fast 1:1 mixing of I+ with an aromatic compound using a microflow system consisting of a T-shaped micromixer and a microtube reactor.

Selective monoiodination of aromatic compounds with electrochemically generated I+ using micromixing

Selective monoiodination of aromatic compounds such as dimethoxybenzene has been successfully achieved with I+, which is generated by anodic oxidation of I2 in acetonitrile, using micromixing. The Royal Society of Chemistry 2006.

PROCESS FOR PRODUCING AROMATIC IODINE COMPOUND

A process for producing an aromatic iodine compound. It has advantages of ease of handling and high safety. By the process, the reaction product having an excellent color tone can be produced in a high yield. The process for aromatic iodine compound production is characterized by introducing an aromatic compound and an active iodizing agent into a flow-through type reactor equipped with a high-speed mixer to continuously replace hydrogen atoms of the aromatic nucleus of the aromatic compound with iodine atoms.

Banana-shaped oligo(aryleneethynylene)s: Synthesis and light-emitting characteristics

(Chemical Equation Presented) Pick of the bunch: Banana-shaped molecules 1 and 2 containing dimethoxybenzene and pyridine units are highly efficient emitters of violet light despite the interruption of the π conjugation because of meta substitution. The c

A facile synthesis of 1,4-dialkoxy-2,5-diiodobenzenes: reaction of dialkoxybenzenes with iodine monochloride in alcoholic solvents

A facile synthesis of 1,4-dialkoxy-2,5-diiodobenzenes via diiodination of the corresponding dialkoxybenzenes with iodine monochloride has been developed. Employment of ah alcoholic solvent as a reaction medium is crucial for attaining a high yield; the reaction in a nonalcoholic solvent usually resulted in a poor yield. The diiodobenzene derivatives are useful intermediates in the synthesis of such advanced materiais as soluble phenylenevinylene polymers anal dialkoxy derivatives of 7,7,8,8-tetracyanoquinodimethane.

Multistep Reversible Redox Systems, LXIII. 2,5-Disubstituted N,N'-Dicyanoquinone Diimines (DCNQIs) - Syntheses, and Redox Properties

Quinones 1a-q and DCNQIs 2a-g have been synthesized in order to investigate substituent effects.It was necessary to employ novel synthetic routes for the introduction of iodine into 1f (7), the trifluoromethyl group into 1g-i, deuterium into 1m-p, and esp

Cation Radicals as Intermediates in Aromatic Halogenation with Iodine Monochloride: Solvent and Salt Effects on the Competition between Chlorination and Iodination

Three distinct classes of substitutional reactivity can be discerned in the halogenation of a series of methyl-substituted methoxybenzenes (ArH) with iodine monochloride (ICl), namely, exclusive iodination, exclusive chlorination, and mixed iodination/chlorination.Spectral studies establish the prior formation of the charge-transfer complex which suffers electron transfer to afford the reactive triad .+,I.,Cl(-)> according to Scheme 1.Separate reactivity studies show that chlorination and iodination can result from the quenching of the aromatic cation radical by chloride and iodine (atom), respectively.Iodination versus chlorination thus represents the competition between radical-pair and ion-pair collapse from the reactive triad, and it is predictably modulated by solvent polarity and added salt.

Rapid brain scanning radiopharmaceutical

A method for detecting the blood flow in animals, particularly in the brain, is provided wherein a detectable amount of a novel radioactive compound of the formula I is administered to one animal: STR1 wherein R1 and R2 are independe