1-CHLORO-5-PHENYLPENTANE

Base Information

• Chemical Name: 1-CHLORO-5-PHENYLPENTANE
• CAS No.: 15733-63-8
• Molecular Formula: C11H15Cl
• Molecular Weight: 182.693
• Hs Code.: 2903999090
• Mol file: 15733-63-8.mol

Synonyms:(5-Chloropentyl)benzene;1-Chloro-5-phenylpentane;5-Phenyl-1-chloropentane;5-Phenylpentyl chloride;

Chemical Property of 1-CHLORO-5-PHENYLPENTANE

Chemical Property:

• Appearance/Colour: cream
• Vapor Pressure: 0.0148mmHg at 25°C
• Refractive Index: 1.5140
• Boiling Point: 265.8 °C at 760 mmHg
• Flash Point: 111.7 °C
• PSA: 0.00000
• Density: 0.997 g/cm³
• LogP: 3.63820
• Storage Temp.: 2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

5-Phenylpentyl chloride ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-CHLORO-5-PHENYLPENTANE

There total 11 articles about 1-CHLORO-5-PHENYLPENTANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

5-phenylpentan-1-ol (10521-91-2) → 5-chloropentylbenzene (15733-63-8)

Guidance literature:

With 2,6-dimethylpyridine; tetraethylammonium chloride; ethanaminium,N-(difluoro-λ⁴-sulfanylidene)-N-ethyl-,tetrafluoroborate; In dichloromethane; at 21 ℃; Inert atmosphere;

DOI:10.1021/ol302496q

Reference yield: 64.0%

5-phenylpent-2-ene (1745-16-0) → 5-chloropentylbenzene (15733-63-8)

Guidance literature:

With dichloro bis(acetonitrile) palladium(II); N-chloro-succinimide; chlorotriisopropylsilane; water; C₁₄H₂₀N₂O₂; triethylamine; In dichloromethane; acetonitrile; at 25 ℃; Schlenk technique; Inert atmosphere; Sealed tube;

DOI:10.1038/s41557-021-00869-x

Reference yield:

6-bromohexanoic acid (4224-70-8) + phenylzinc chloride (28557-00-8) → (5-bromopentyl)benzene (14469-83-1) + biphenyl (92-52-4,1594-86-1) + 5-chloropentylbenzene (15733-63-8)

Guidance literature:

6-bromohexanoic acid; With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In tetrahydrofuran; at 25 ℃; for 0.5h; Inert atmosphere;

With (1,2-dimethoxyethane)dichloronickel(II); 4,4'-di-tert-butyl-2,2'-bipyridine; In N,N-dimethyl-formamide; at 25 ℃; for 0.0833333h; Inert atmosphere;

phenylzinc chloride; In tetrahydrofuran; N,N-dimethyl-formamide; at 25 ℃; for 12h;

DOI:10.1021/jacs.6b07172

upstream raw materials:

5-phenylpentan-1-ol

1,5-dichloropentane

benzene

3-phenylpropylmagnesium bromide

Downstream raw materials:

Essigsaeure-(5-phenylpentyl)ester

(5-phenoxypentyl)benzene

pentylbenzene

1,10-diphenyldecane