2,2'-BIS(HYDROXYMETHYL)DIPHENYL ETHER

Base Information

• Chemical Name: 2,2'-BIS(HYDROXYMETHYL)DIPHENYL ETHER
• CAS No.: 10038-40-1
• Molecular Formula: C14H14O3
• Molecular Weight: 230.263
• Hs Code.: 2909499000
• Mol file: 10038-40-1.mol

Synonyms:Benzylalcohol, 2,2'-oxydi- (7CI,8CI);2,2'-Bis(hydroxymethyl)diphenyl ether;2,2'-Oxybis[benzenemethanol];2,2'-Oxydi(benzyl alcohol);

Chemical Property of 2,2'-BIS(HYDROXYMETHYL)DIPHENYL ETHER

Chemical Property:

• Melting Point: 99°C
• Boiling Point: 385.9±37.0 °C(Predicted)
• PKA: 14.06±0.10(Predicted)
• Flash Point: 187.2oC
• PSA: 49.69000
• Density: 1.227 g/cm³
• LogP: 2.46350
• Solubility.: almost transparency in Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,2'-Bis(hydroxymethyl)diphenyl Ether ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2'-BIS(HYDROXYMETHYL)DIPHENYL ETHER

There total 8 articles about 2,2'-BIS(HYDROXYMETHYL)DIPHENYL ETHER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,2'-oxybis(benzaldehyde) (49590-51-4) → [oxybis(2,1-phenylene)]dimethanol (10038-40-1)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 20 ℃; for 1.25h; Cooling with ice;

DOI:10.1002/chem.201902458

Reference yield: 48.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + diphenylether (101-84-8) → [oxybis(2,1-phenylene)]dimethanol (10038-40-1)

Guidance literature:

diphenylether; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In hexane; at 0 ℃; for 24h;

formaldehyd; In hexane; for 48h; Reflux;

DOI:10.1016/j.poly.2011.11.053

Reference yield:

2,2'-oxy-di-benzoyl chloride (32852-70-3) → [oxybis(2,1-phenylene)]dimethanol (10038-40-1)

Guidance literature:

With sodium tetrahydroborate; In diethylene glycol dimethyl ether; for 0.0833333h; Yield given; Ambient temperature;

DOI:10.1021/jm00106a003

upstream raw materials:

2,2'-Oxybisbenzoesaeure-dimethylester

2,2'-oxy-di-benzoyl chloride

2,2'-oxybis(benzoic acid)

formaldehyd

Downstream raw materials:

2,2'-oxybisbenzeneacetic acid

2,2'-oxybisbenzeneacetonitrile

O(C₆H₄CH₂SH)2

2,2'-oxybis(benzaldehyde)

Refernces

• 1、 Cervantes-Reyes, Alejandro,Rominger, Frank,Rudolph, Matthias,Hashmi, A. Stephen K.. "Gold(I) Complexes Stabilized by Nine- and Ten-Membered N-Heterocyclic Carbene Ligands". . p. 11745 - 11757. Retrieved 2019.
• 2、 Rewcastle, Gordon W.,Atwell, Graham J.,Palmer, Brian D.,Boyd, Peter D. W.,Baguley, Bruce C.,Denny, William A.. "Potential Antitumor Agents. 62. Structure Activity Relationships for Tricyclic Compounds Related to the Colon Tumor Active Drug 9-Oxo-9H-xanthene-4-acetic Acid". . p. 491 - 496. Retrieved 2007/10/02.