2-(TRIMETHYLSILYLETHYNYL)PYRIDINE

Base Information

Chemical Name:2-(TRIMETHYLSILYLETHYNYL)PYRIDINE
CAS No.:86521-05-3
Molecular Formula:C10H13NSi
Molecular Weight:175.305
Hs Code.:29333990
Mol file:86521-05-3.mol

Synonyms:Pyridine,2-[(trimethylsilyl)ethynyl]- (9CI);2-(Trimethylsilylethynyl)pyridine;Trimethyl[(pyridin-2-yl)ethynyl]silane;

Suppliers and Price of 2-(TRIMETHYLSILYLETHYNYL)PYRIDINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(Trimethylsilylethynyl)pyridine
500mg
$ 75.00

TCI Chemical
2-[(Trimethylsilyl)ethynyl]pyridine
1G
$ 41.00

TCI Chemical
2-[(Trimethylsilyl)ethynyl]pyridine
5G
$ 140.00

Synthonix
2-((Trimethylsilyl)ethynyl)pyridine 95+%
10g
$ 160.00

Synthonix
2-((Trimethylsilyl)ethynyl)pyridine 95+%
5g
$ 90.00

Synthonix
2-((Trimethylsilyl)ethynyl)pyridine 95+%
1g
$ 30.00

Synthonix
2-((Trimethylsilyl)ethynyl)pyridine 95+%
25g
$ 310.00

GFS CHEMICALS
2-TMSETHYNYLPYRIDINE
25 G
$ 375.25

Crysdot
2-((Trimethylsilyl)ethynyl)pyridine 95+%
25g
$ 211.00

Chem-Impex
2-[(Trimethylsilyl)ethynyl]pyridine,98%(GC) 98%(GC)
1G
$ 44.80

Total 32 raw suppliers

Chemical Property of 2-(TRIMETHYLSILYLETHYNYL)PYRIDINE

Chemical Property:

Appearance/Colour:Clear colorless to yellow liquid
Vapor Pressure:0.19mmHg at 25°C
Melting Point:42 °C
Refractive Index:1.5330
Boiling Point:85 °C
PKA:4.29±0.19(Predicted)
Flash Point:85-86°C/1mm
PSA：12.89000
Density:0.95g/cm³
LogP:2.31050
Storage Temp.:Refrigerator (+4°C)
Water Solubility.:Insoluble in water.

Purity/Quality:

97% ^*data from raw suppliers

2-(Trimethylsilylethynyl)pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s): R36/38:Irritating to eyes and skin.;
Hazard Codes:R36/38:Irritating to eyes and skin.;
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-(Trimethylsilylethynyl)pyridine is used as a pharmaceutical intermediate.

Technology Process of 2-(TRIMETHYLSILYLETHYNYL)PYRIDINE

There total 10 articles about 2-(TRIMETHYLSILYLETHYNYL)PYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 109-04-6
2-bromo-pyridine

: 1066-54-2
trimethylsilylacetylene

: 86521-05-3
2-(trimethylsilylethynyl)pyridine

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; at 70 ℃; for 3h;
DOI:10.1055/s-1983-30319

Reference yield: 90.0%

: 1945-84-2
2-ethynylpyridine

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 86521-05-3
2-(trimethylsilylethynyl)pyridine

Guidance literature:: With sodium hydride; 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride; In neat (no solvent); at 31 - 33 ℃; for 0.416667h;
DOI:10.1039/c4ra08727e

Reference yield: 83.0%

: 109-09-1
2-chloropyridine

: 1066-54-2
trimethylsilylacetylene

: 86521-05-3
2-(trimethylsilylethynyl)pyridine

Guidance literature:: With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; for 46h; Inert atmosphere; Reflux;
DOI:10.1246/cl.2011.925