4-(4-carboxyphenyl)-2,6-bipyrazin-2-ylpyridine

Base Information

• Chemical Name: 4-(4-carboxyphenyl)-2,6-bipyrazin-2-ylpyridine
• CAS No.: 1239444-46-2
• Molecular Formula: C₂₀H₁₃N₅O₂
• Molecular Weight: 355.356
• Mol file: 1239444-46-2.mol

Synonyms:4-(4-carboxyphenyl)-2,6-bipyrazin-2-ylpyridine

Chemical Property of 4-(4-carboxyphenyl)-2,6-bipyrazin-2-ylpyridine

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 4-(4-carboxyphenyl)-2,6-bipyrazin-2-ylpyridine

There total 1 articles about 4-(4-carboxyphenyl)-2,6-bipyrazin-2-ylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

acetylpyrazine (22047-25-2) + 4-Carboxybenzaldehyde (619-66-9) → 4-(4-carboxyphenyl)-2,6-bipyrazin-2-ylpyridine (1239444-46-2)

Guidance literature:

acetylpyrazine; 4-Carboxybenzaldehyde; With ammonium hydroxide; potassium hydroxide; In methanol; at 20 ℃; for 72h;

With hydrogenchloride; In methanol; water; pH=2;

DOI:10.1002/ejic.201000122

Reference yield: 58.0%

ammonium hexafluorophosphate + ruthenium(III) chloride trihydrate (14898-67-0) + 4-(4-carboxyphenyl)-2,6-bipyrazin-2-ylpyridine (1239444-46-2) → bis[4-(4-carboxyphenyl)-2,6-dipyrazin-2-ylpyridine]ruthenium(II) bis(hexafluorophosphate)

Guidance literature:

With AgBF₄; In water; N,N-dimethyl-formamide; RuCl3*3H2O and AgBF4 (1:4) dissolved in DMF, refluxed for 3 h, treated with 2 equiv. of ligand, refluxed for 3 d, filtered (celite), treated with NH4PF6 in H2O, kept at room temp. overnight; filtered, washed (H2O, Et2O), collected with hot CN3CN with a few drops of aq.HPF6, concd., pptd.(Et2O), elem. anal.;

DOI:10.1002/ejic.201000122

Reference yield: 43.0%

4-(4-carboxyphenyl)-2,6-bipyrazin-2-ylpyridine (1239444-46-2) + uranyl(VI) acetate dihydrate → 2C20H12N5O2(1-)*O2U(2+)

Guidance literature:

In ethanol; water; at 20 - 120 ℃; for 76h; pH=4; Autoclave; High pressure;

DOI:10.1039/C6NJ03933B

upstream raw materials:

acetylpyrazine

4-Carboxybenzaldehyde