3-indole

Base Information

• Chemical Name: 3-indole
• CAS No.: 86427-25-0
• Molecular Formula: C₁₆H₁₂Cl₂N₂
• Molecular Weight: 303.191

Synonyms:3-indole

Chemical Property of 3-indole

Chemical Property:

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Technology Process of 3-indole

There total 1 articles about 3-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

Indole-3-carboxaldehyde (487-89-8,1228547-52-1) + 2,4-dichloro-benzenemethanamine (95-00-1) → 3-indole (86427-25-0)

Guidance literature:

With acetic acid; In ethanol; for 6h; Heating;

Reference yield: 60.0%

3-indole (86427-25-0) + mercaptoacetic acid (68-11-1) → 3-<3-(2,4-dichlorobenzyl)-4-oxo-3-thiazolidinyl>indole (86427-40-9)

Guidance literature:

In benzene; Ambient temperature;

Reference yield: 40.0%

3-indole (86427-25-0) + chloroacetyl chloride (79-04-9) → 3-<1-(2,4-dichlorobenzyl)-3-chloro-2-oxo-azetidinyl>indole (86427-32-9)

Guidance literature:

With triethylamine; In 1,4-dioxane; for 3h; Heating;

upstream raw materials:

Indole-3-carboxaldehyde

2,4-dichloro-benzenemethanamine

Downstream raw materials:

3-<3-(2,4-dichlorobenzyl)-4-oxo-3-thiazolidinyl>indole

3-<1-(2,4-dichlorobenzyl)-3-chloro-2-oxo-azetidinyl>indole

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