3,3'-[1,2-ethanediylbis[[[(1,1-dimethylethoxy)carbonyl]imino]-2,1-ethanediyliminocarbonyl-4,2-thiazolediyl]]-bis[4-hydroxy]benzoic acid dimethyl ester

Base Information

• Chemical Name: 3,3'-[1,2-ethanediylbis[[[(1,1-dimethylethoxy)carbonyl]imino]-2,1-ethanediyliminocarbonyl-4,2-thiazolediyl]]-bis[4-hydroxy]benzoic acid dimethyl ester
• CAS No.: 1148627-82-0
• Molecular Formula: C₄₀H₄₈N₆O₁₂S₂
• Molecular Weight: 868.986
• Mol file: 1148627-82-0.mol

Synonyms:3,3'-[1,2-ethanediylbis[[[(1,1-dimethylethoxy)carbonyl]imino]-2,1-ethanediyliminocarbonyl-4,2-thiazolediyl]]-bis[4-hydroxy]benzoic acid dimethyl ester

Chemical Property of 3,3'-[1,2-ethanediylbis[[[(1,1-dimethylethoxy)carbonyl]imino]-2,1-ethanediyliminocarbonyl-4,2-thiazolediyl]]-bis[4-hydroxy]benzoic acid dimethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,3'-[1,2-ethanediylbis[[[(1,1-dimethylethoxy)carbonyl]imino]-2,1-ethanediyliminocarbonyl-4,2-thiazolediyl]]-bis[4-hydroxy]benzoic acid dimethyl ester

There total 2 articles about 3,3'-[1,2-ethanediylbis[[[(1,1-dimethylethoxy)carbonyl]imino]-2,1-ethanediyliminocarbonyl-4,2-thiazolediyl]]-bis[4-hydroxy]benzoic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C40H52N6O12S2 (1148627-83-1) → 3,3'-[1,2-ethanediylbis[[[(1,1-dimethylethoxy)carbonyl]imino]-2,1-ethanediyliminocarbonyl-4,2-thiazolediyl]]-bis[4-hydroxy]benzoic acid dimethyl ester (1148627-82-0)

Guidance literature:

With Bromotrichloromethane; 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 0 - 25 ℃; for 16h; Inert atmosphere;

DOI:10.1016/j.tet.2011.01.008

Reference yield:

tert-butyl N-(2-aminoethyl)-N-[2-(2-aminoethyl(tert-butoxycarbonyl)amino)ethyl]carbamate (206531-21-7) → 3,3'-[1,2-ethanediylbis[[[(1,1-dimethylethoxy)carbonyl]imino]-2,1-ethanediyliminocarbonyl-4,2-thiazolediyl]]-bis[4-hydroxy]benzoic acid dimethyl ester (1148627-82-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 16 h / 20 °C / Inert atmosphere

2: Bromotrichloromethane; 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 16 h / 0 - 25 °C / Inert atmosphere

With Bromotrichloromethane; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane;

DOI:10.1016/j.tet.2011.01.008

Reference yield: 80.0%

3,3'-[1,2-ethanediylbis[[[(1,1-dimethylethoxy)carbonyl]imino]-2,1-ethanediyliminocarbonyl-4,2-thiazolediyl]]-bis[4-hydroxy]benzoic acid dimethyl ester (1148627-82-0) + trifluoroacetic acid (76-05-1) → 2C2HF3O2*C30H32N6O8S2

Guidance literature:

In dichloromethane; at 20 ℃; for 5h;

DOI:10.1016/j.tet.2011.01.008

upstream raw materials:

C₄₀H₅₂N₆O₁₂S₂

tert-butyl N-(2-aminoethyl)-N-[2-(2-aminoethyl(tert-butoxycarbonyl)amino)ethyl]carbamate

Downstream raw materials:

3,3'-[1,2-ethanediylbis[[[(1,1-dimethylethoxy)carbonyl]imino]-2,1-ethanediyliminocarbonothioyl-4,2-thiazolediyl]]-bis[4-hydroxy]benzoic acid dimethyl ester

3,3'-[1,2-ethanediylbis[[[(1,1-dimethylethoxy)carbonyl]imino]-2,1-ethanediyliminocarbonyl-4,2-thiazolediyl]]-bis[4-hydroxy]benzoic acid

3,3'-[1,2-ethanediylbis[[[(1,1-dimethylethoxy)carbonyl]imino]-2,1-ethanediyliminocarbonothioyl-4,2-thiazolediyl]]-bis[4-hydroxy]benzoic acid