1-ethyl-2-methyl-2-(tosylcarbamoyl)-1-[(trideuteromethyl)tosylcarbamoyl]hydrazine

Base Information

• Chemical Name: 1-ethyl-2-methyl-2-(tosylcarbamoyl)-1-[(trideuteromethyl)tosylcarbamoyl]hydrazine
• CAS No.: 220079-57-2
• Molecular Formula: C₂₀H₂₆N₄O₆S₂
• Molecular Weight: 485.558
• Mol file: 220079-57-2.mol

Synonyms:1-ethyl-2-methyl-2-(tosylcarbamoyl)-1-[(trideuteromethyl)tosylcarbamoyl]hydrazine

Chemical Property of 1-ethyl-2-methyl-2-(tosylcarbamoyl)-1-[(trideuteromethyl)tosylcarbamoyl]hydrazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-ethyl-2-methyl-2-(tosylcarbamoyl)-1-[(trideuteromethyl)tosylcarbamoyl]hydrazine

There total 4 articles about 1-ethyl-2-methyl-2-(tosylcarbamoyl)-1-[(trideuteromethyl)tosylcarbamoyl]hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Tosyl isocyanate (4083-64-1) → 1-ethyl-2-methyl-2-(tosylcarbamoyl)-1-[(trideuteromethyl)tosylcarbamoyl]hydrazine (220079-57-2)

Guidance literature:

Multi-step reaction with 4 steps

1: 99 percent / CH₂Cl₂

2: 79 percent / Ph₃P, DEAD / tetrahydrofuran

3: 97 percent / H₂ / 5percent Pd/C / methanol

4: CH₂Cl₂ / 2 h / Ambient temperature

With hydrogen; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1055/s-1998-2217

Reference yield:

N'-Ethyl-N-methyl-N'-(toluene-4-sulfonylaminocarbonyl)-hydrazinecarboxylic acid benzyl ester (220079-41-4) → 1-ethyl-2-methyl-2-(tosylcarbamoyl)-1-[(trideuteromethyl)tosylcarbamoyl]hydrazine (220079-57-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 79 percent / Ph₃P, DEAD / tetrahydrofuran

2: 97 percent / H₂ / 5percent Pd/C / methanol

3: CH₂Cl₂ / 2 h / Ambient temperature

With hydrogen; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1055/s-1998-2217

Reference yield:

1-(benzyloxycarbonyl)-2-ethyl-1-methyl-2-[(trideuteromethyl)tosylcarbamoyl]hydrazine (220079-44-7) → 1-ethyl-2-methyl-2-(tosylcarbamoyl)-1-[(trideuteromethyl)tosylcarbamoyl]hydrazine (220079-57-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 97 percent / H₂ / 5percent Pd/C / methanol

2: CH₂Cl₂ / 2 h / Ambient temperature

With hydrogen; palladium on activated charcoal; In methanol; dichloromethane;

DOI:10.1055/s-1998-2217

upstream raw materials:

Tosyl isocyanate

C₁₂H₁₆⁽²⁾H₃N₃O₃S

N'-Ethyl-N-methyl-N'-(toluene-4-sulfonylaminocarbonyl)-hydrazinecarboxylic acid benzyl ester

1-(benzyloxycarbonyl)-2-ethyl-1-methyl-2-[(trideuteromethyl)tosylcarbamoyl]hydrazine