a-(4-Methylphenyl)-4-piperidinemethanol

Base Information

Chemical Name:a-(4-Methylphenyl)-4-piperidinemethanol
CAS No.:38081-61-7
Molecular Formula:C₁₃H₁₉NO
Molecular Weight:205.3
Hs Code.:

Synonyms:a-(4-Methylphenyl)-4-piperidinemethanol;38081-61-7

Suppliers and Price of a-(4-Methylphenyl)-4-piperidinemethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(4-METHYLPHENYL)(PIPERIDIN-4-YL)METHANOL 95.00%
5MG
$ 497.13

Acrotein
a-(4-Methylphenyl)-4-piperidinemethanol 97%
1g
$ 330.00

Acrotein
a-(4-Methylphenyl)-4-piperidinemethanol 97%
0.5g
$ 220.00

Acrotein
a-(4-Methylphenyl)-4-piperidinemethanol 97%
0.25g
$ 146.67

Total 2 raw suppliers

Chemical Property of a-(4-Methylphenyl)-4-piperidinemethanol

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:205.146664230
Heavy Atom Count:15
Complexity:181

Purity/Quality:

99% ^*data from raw suppliers

(4-METHYLPHENYL)(PIPERIDIN-4-YL)METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C(C2CCNCC2)O

Technology Process of a-(4-Methylphenyl)-4-piperidinemethanol

There total 6 articles about a-(4-Methylphenyl)-4-piperidinemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 74130-04-4
4-(4-methylbenzoyl)-piperidine

: 38081-61-7
(4-methylphenyl)(piperidin-4-yl)methanol

Guidance literature:: With sodium tetrahydroborate; In methanol; water; for 2h; Heating;
DOI:10.1021/jm0309349

Reference yield:

: 4395-98-6
4-cyanopiperidine

: 38081-61-7
(4-methylphenyl)(piperidin-4-yl)methanol

Guidance literature:: Multi-step reaction with 4 steps

1.1: 79 percent / NaHCO₃ / 20 h / 20 °C

2.1: Mg; I₂ / diethyl ether / Heating

2.2: diethyl ether / Heating

3.1: aq.HCl / methanol / Heating

4.1: 95 percent / NaBH₄ / methanol; H₂O / 2 h / Heating

With hydrogenchloride; sodium tetrahydroborate; iodine; sodium hydrogencarbonate; magnesium; In methanol; diethyl ether; water;
DOI:10.1021/jm0309349

Reference yield:

: 39546-32-2
4-carboxamidopiperidine

: 38081-61-7
(4-methylphenyl)(piperidin-4-yl)methanol

Guidance literature:: Multi-step reaction with 5 steps

1.1: 86 percent / SOCl₂ / 3 h / Heating

2.1: 79 percent / NaHCO₃ / 20 h / 20 °C

3.1: Mg; I₂ / diethyl ether / Heating

3.2: diethyl ether / Heating

4.1: aq.HCl / methanol / Heating

5.1: 95 percent / NaBH₄ / methanol; H₂O / 2 h / Heating

With hydrogenchloride; sodium tetrahydroborate; thionyl chloride; iodine; sodium hydrogencarbonate; magnesium; In methanol; diethyl ether; water;
DOI:10.1021/jm0309349