diethyl N-<4-<<(2,4-diamino-6-pteridinyl)methyl>octylamino>benzoyl>-L-glutamate

Base Information

Chemical Name:diethyl N-<4-<<(2,4-diamino-6-pteridinyl)methyl>octylamino>benzoyl>-L-glutamate
CAS No.:82318-22-7
Molecular Formula:C₃₁H₄₄N₈O₅
Molecular Weight:608.741
Hs Code.:

Synonyms:diethyl N-<4-<<(2,4-diamino-6-pteridinyl)methyl>octylamino>benzoyl>-L-glutamate

Suppliers and Price of diethyl N-<4-<<(2,4-diamino-6-pteridinyl)methyl>octylamino>benzoyl>-L-glutamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of diethyl N-<4-<<(2,4-diamino-6-pteridinyl)methyl>octylamino>benzoyl>-L-glutamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of diethyl N-<4-<<(2,4-diamino-6-pteridinyl)methyl>octylamino>benzoyl>-L-glutamate

There total 4 articles about diethyl N-<4-<<(2,4-diamino-6-pteridinyl)methyl>octylamino>benzoyl>-L-glutamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 52853-40-4
6-bromomethyl-2,4-diaminopteridine hydrobromide

: 82318-20-5
diethyl N-<4-(octylamino)benzoyl>-L-glutamate

: 82318-22-7
diethyl N-<4-<<(2,4-diamino-6-pteridinyl)methyl>octylamino>benzoyl>-L-glutamate

Guidance literature:: In N,N-dimethyl acetamide; 1.) from 50 to 55 deg C, 6 h, 2.) 25 deg C, 18 h;
DOI:10.1021/jm00349a024

Reference yield:

: 16450-41-2
L-glutamic acid diethyl ester

: 82318-22-7
diethyl N-<4-<<(2,4-diamino-6-pteridinyl)methyl>octylamino>benzoyl>-L-glutamate

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent

2: 43 percent / HBr, CH₃COOH, phenol

3: 67 percent / N,N-dimethyl-acetamide / 1.) from 50 to 55 deg C, 6 h, 2.) 25 deg C, 18 h

With hydrogen bromide; acetic acid; phenol; In N,N-dimethyl acetamide;
DOI:10.1021/jm00349a024

Reference yield:

: 4-[Octyl-(toluene-4-sulfonyl)-amino]-benzoyl chloride

: 82318-22-7
diethyl N-<4-<<(2,4-diamino-6-pteridinyl)methyl>octylamino>benzoyl>-L-glutamate

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent

2: 43 percent / HBr, CH₃COOH, phenol

3: 67 percent / N,N-dimethyl-acetamide / 1.) from 50 to 55 deg C, 6 h, 2.) 25 deg C, 18 h

With hydrogen bromide; acetic acid; phenol; In N,N-dimethyl acetamide;
DOI:10.1021/jm00349a024