LITHIUM SALICYLATE

Base Information

• Chemical Name: LITHIUM SALICYLATE
• CAS No.: 552-38-5
• Molecular Formula: C7H5LiO3
• Molecular Weight: 144.056
• Hs Code.: 2918219000
• Mol file: 552-38-5.mol

Synonyms:Benzoicacid, 2-hydroxy-, monolithium salt (9CI);Lithium salicylate (7CI);Salicylicacid, monolithium salt (8CI);

Chemical Property of LITHIUM SALICYLATE

Chemical Property:

• Melting Point: >350 °C(lit.)
• Boiling Point: 336.3 °C at 760 mmHg
• Flash Point: 144.5 °C
• PSA: 60.36000
• Density: 1.428[at 20℃]
• LogP: -0.24430
• Water Solubility.: Soluble in water

Purity/Quality:

99.9% ^*data from raw suppliers

Lithium salicylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36/38
• Safety Statements: 22-26-36

MSDS Files:

Useful:

• Description: Lithium salicylate is the lithium salt of salicylate, which is a kind of organic acid. Lithium salicylate may be a good alternative for treating bipolar disorder and other neuropsychiatric conditions as it was recently found that oral lithium salicylate was able to produce steady lithium levels for up to 48 hours in rats – without the toxic side effects typically linked with the rapid absorption of current FDA-approved lithium carbonate. It is also proposed that lithium salicylate is most effective drug in reducing self-harm and suicide. The therapeutic effect of lithium salicylate allows for its application in diuretics. In addition, with the aid of its catalysis effect, this chemical can be employed as the catalysts for chemiluminescent system or trimer catalyst for aliphatic and aromatic isocyanates.

Technology Process of LITHIUM SALICYLATE

There total 1 articles about LITHIUM SALICYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

salicylic acid (69-72-7,25496-36-0,8052-31-1) → lithium salicylate (552-38-5)

Guidance literature:

With lithium carbonate; In water; Acidic conditions;

DOI:10.1002/jms.3384

Reference yield: 99.0%

lithium salicylate (552-38-5) → Lithium Salicylate Proline + L-proline (147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7)

Guidance literature:

Reference yield: 91.0%

cobalt(II) chloride hexahydrate + tri-n-butyl(4-vinylbenzyl)phosphonium chloride + lithium salicylate (552-38-5) → bis[tributyl(4-vinylbenzyl)phosphonium][cobalt(II) bis(salicylate)]

Guidance literature:

In methanol; water; at 20 ℃; for 24h;

DOI:10.1002/pola.28623

upstream raw materials:

salicylic acid

Downstream raw materials:

phenol

Co^II(OH)(salicylate)(H₂O)

L-proline

Refernces