(S)-4-(4-chloro-6-(2-(methylsulfonyl)phenyl)-1,3,5-triazin-2-yl)-3-methylmorpholine

Base Information

Chemical Name:(S)-4-(4-chloro-6-(2-(methylsulfonyl)phenyl)-1,3,5-triazin-2-yl)-3-methylmorpholine
CAS No.:1428532-48-2
Molecular Formula:C₁₅H₁₇ClN₄O₃S
Molecular Weight:368.844
Hs Code.:

Synonyms:(S)-4-(4-chloro-6-(2-(methylsulfonyl)phenyl)-1,3,5-triazin-2-yl)-3-methylmorpholine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-4-(4-chloro-6-(2-(methylsulfonyl)phenyl)-1,3,5-triazin-2-yl)-3-methylmorpholine

Chemical Property:

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Technology Process of (S)-4-(4-chloro-6-(2-(methylsulfonyl)phenyl)-1,3,5-triazin-2-yl)-3-methylmorpholine

There total 2 articles about (S)-4-(4-chloro-6-(2-(methylsulfonyl)phenyl)-1,3,5-triazin-2-yl)-3-methylmorpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1428532-47-1
(S)-4-(4,6-dichloro-1,3,5-triazin-2-yl)-3-methylmorpholine

: (2-(methylsulfonyl)-phenyl)boronic acid

: 1428532-48-2
(S)-4-(4-chloro-6-(2-(methylsulfonyl)phenyl)-1,3,5-triazin-2-yl)-3-methylmorpholine

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; In 1,2-dimethoxyethane; water; at 60 ℃; for 0.416667h; Microwave irradiation;

Reference yield:

: 350595-57-2
(S)-3-methylmorpholine

: 1428532-48-2
(S)-4-(4-chloro-6-(2-(methylsulfonyl)phenyl)-1,3,5-triazin-2-yl)-3-methylmorpholine

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane / 0.33 h / 20 °C

2: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate / 1,2-dimethoxyethane; water / 0.42 h / 60 °C / Microwave irradiation

With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; In 1,2-dimethoxyethane; dichloromethane; water;

Reference yield: 15.0%

: 1009629-18-8
4-(3-cyclopropylureido)phenyl boronic acid

: 1428532-48-2
(S)-4-(4-chloro-6-(2-(methylsulfonyl)phenyl)-1,3,5-triazin-2-yl)-3-methylmorpholine

: 1428531-93-4
(S)-1-cyclopropyl-3-(4-(4-(3-methylmorpholino)-6-(2-(methylsulfonyl)phenyl)-1,3,5-triazin-2-yl)phenyl)urea

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; In 1,2-dimethoxyethane; water; at 100 ℃; for 0.5h; Microwave irradiation;