methyl [4-(4-[methoxycarbonylmethoxy]phenyldithio)phenoxy]acetate

Base Information

• Chemical Name: methyl [4-(4-[methoxycarbonylmethoxy]phenyldithio)phenoxy]acetate
• CAS No.: 167012-47-7
• Molecular Formula: C₁₈H₁₈O₆S₂
• Molecular Weight: 394.469
• Mol file: 167012-47-7.mol

Synonyms:methyl [4-(4-[methoxycarbonylmethoxy]phenyldithio)phenoxy]acetate

Chemical Property of methyl [4-(4-[methoxycarbonylmethoxy]phenyldithio)phenoxy]acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl [4-(4-[methoxycarbonylmethoxy]phenyldithio)phenoxy]acetate

There total 2 articles about methyl [4-(4-[methoxycarbonylmethoxy]phenyldithio)phenoxy]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

bis(4-hydroxyphenyl)disulfide (15015-57-3) + bromoacetic acid methyl ester (96-32-2) → methyl [4-(4-[methoxycarbonylmethoxy]phenyldithio)phenoxy]acetate (167012-47-7)

Guidance literature:

bis(4-hydroxyphenyl)disulfide; With sodium hydride; In N,N-dimethyl-formamide;

bromoacetic acid methyl ester; In N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2005.09.060

Reference yield:

4-sulfanylphenol (637-89-8) → methyl [4-(4-[methoxycarbonylmethoxy]phenyldithio)phenoxy]acetate (167012-47-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 93 percent / dimethylsulfoxide

2.1: NaH / dimethylformamide

2.2: 82 percent / dimethylformamide

With sodium hydride; In dimethyl sulfoxide; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2005.09.060

Reference yield: 85.0%

methyl [4-(4-[methoxycarbonylmethoxy]phenyldithio)phenoxy]acetate (167012-47-7) → (4-Mercapto-phenoxy)-acetic Acid Methyl Ester (1706-60-1)

Guidance literature:

With hydrogenchloride; zinc; In dichloromethane; at 25 ℃; for 2h;

DOI:10.1039/b612235c

upstream raw materials:

bis(4-hydroxyphenyl)disulfide

bromoacetic acid methyl ester

4-sulfanylphenol

Downstream raw materials:

(4-Mercapto-phenoxy)-acetic Acid Methyl Ester

methyl 2-{4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]phenoxy}acetate

{4-[4-furan-2-yl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethylsulfanyl]-phenoxy}-acetic acid methyl ester

{4-[4-phenyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethylsulfanyl]-phenoxy}-acetic acid methyl ester