α-(bistrifluoromethylamino-oxy)benzyl cyanide

Base Information

• Chemical Name: α-(bistrifluoromethylamino-oxy)benzyl cyanide
• CAS No.: 77228-18-3
• Molecular Formula: C₁₀H₆F₆N₂O
• Molecular Weight: 284.161
• Mol file: 77228-18-3.mol

Synonyms:α-(bistrifluoromethylamino-oxy)benzyl cyanide

Chemical Property of α-(bistrifluoromethylamino-oxy)benzyl cyanide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of α-(bistrifluoromethylamino-oxy)benzyl cyanide

There total 2 articles about α-(bistrifluoromethylamino-oxy)benzyl cyanide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

phenylacetonitrile (140-29-4) → benzoyl cyanide (613-90-1) + N,N-bis(trifluoromethyl)hydroxylamine (359-63-7) + perfluoro(2,4-dimethyl-3-oxa-2,4-diazapentane) (6141-72-6) + α-(bistrifluoromethylamino-oxy)benzyl cyanide (77228-18-3)

Guidance literature:

With bis-trifluoromethyl-aminooxyl; at 20 ℃; for 0.5h;

DOI:10.1039/P19810000455

Reference yield: 81.0%

bis-trifluoromethyl-aminooxyl (2154-71-4) + phenylacetonitrile (140-29-4) → benzoyl cyanide (613-90-1) + N,N-bis(trifluoromethyl)hydroxylamine (359-63-7) + perfluoro(2,4-dimethyl-3-oxa-2,4-diazapentane) (6141-72-6) + α-(bistrifluoromethylamino-oxy)benzyl cyanide (77228-18-3)

Guidance literature:

at 20 ℃; for 0.5h; Mechanism; reactions with other benzyl derivatives (PhCH₂Cl, PhCH₂N₃, and PhCH₂OH);

DOI:10.1039/P19810000455

Reference yield: 28.0%

α-(bistrifluoromethylamino-oxy)benzyl cyanide (77228-18-3) → benzoyl cyanide (613-90-1) + N,N-bis(trifluoromethyl)hydroxylamine (359-63-7) + perfluoro(2,4-dimethyl-3-oxa-2,4-diazapentane) (6141-72-6) + αα-bis(bistrifluoromethylamino-oxy)benzyl cyanide (77228-19-4)

Guidance literature:

With bis-trifluoromethyl-aminooxyl; at 20 ℃; for 5h;

DOI:10.1039/P19810000455

upstream raw materials:

bis-trifluoromethyl-aminooxyl

phenylacetonitrile

Downstream raw materials:

benzoyl cyanide

N,N-bis(trifluoromethyl)hydroxylamine

perfluoro(2,4-dimethyl-3-oxa-2,4-diazapentane)

αα-bis(bistrifluoromethylamino-oxy)benzyl cyanide

Refernces