3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-6-O-(2'-O-benzoyl-3',4',6'-tri-O-benzyl-α-D-mannopyranosyl)-D(L)-myo-inositol

Base Information

• Chemical Name: 3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-6-O-(2'-O-benzoyl-3',4',6'-tri-O-benzyl-α-D-mannopyranosyl)-D(L)-myo-inositol
• CAS No.: 132360-48-6
• Molecular Formula: C₆₇H₇₀O₁₂
• Molecular Weight: 1067.29
• Mol file: 132360-48-6.mol

Synonyms:3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-6-O-(2'-O-benzoyl-3',4',6'-tri-O-benzyl-α-D-mannopyranosyl)-D(L)-myo-inositol

Chemical Property of 3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-6-O-(2'-O-benzoyl-3',4',6'-tri-O-benzyl-α-D-mannopyranosyl)-D(L)-myo-inositol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-6-O-(2'-O-benzoyl-3',4',6'-tri-O-benzyl-α-D-mannopyranosyl)-D(L)-myo-inositol

There total 10 articles about 3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-6-O-(2'-O-benzoyl-3',4',6'-tri-O-benzyl-α-D-mannopyranosyl)-D(L)-myo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

ethyl 2-O-benzoyl-3,4,6-tri-O-benzyl-1-thio-α-D-mannopyranoside (132360-46-4) + 3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-D(L)-myo-inositol (132405-98-2,133162-49-9) → 3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-6-O-(2'-O-benzoyl-3',4',6'-tri-O-benzyl-α-D-mannopyranosyl)-D(L)-myo-inositol (132360-48-6)

Guidance literature:

With N-iodo-succinimide; molecular sieve; trifluorormethanesulfonic acid; In diethyl ether; 1,2-dichloro-ethane; at 0 ℃; for 0.25h;

DOI:10.1016/S0040-4020(01)81480-0

Reference yield: 95.0%

1D-3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-myo-inositol (133162-49-9) + 3,4,6-tri-O-benzyl-β-D-mannopyranose 1,2-(pent-4-enyl orthobenzoate) (125392-62-3) → 3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-6-O-(2'-O-benzoyl-3',4',6'-tri-O-benzyl-α-D-mannopyranosyl)-D(L)-myo-inositol (132360-48-6)

Guidance literature:

With N-iodo-succinimide; boron trifluoride diethyl etherate; In dichloromethane; at 0 ℃; for 0.333333h;

DOI:10.1016/S0040-4039(02)01590-3

Reference yield: 73.0%

1D-3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-myo-inositol (133162-49-9) + (2R,3aS,5R,6R,7S,7aS)-6,7-Bis-benzyloxy-5-benzyloxymethyl-2-pent-4-enyloxy-2-phenyl-tetrahydro-[1,3]dioxolo[4,5-b]pyran → 3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-6-O-(2'-O-benzoyl-3',4',6'-tri-O-benzyl-α-D-mannopyranosyl)-D(L)-myo-inositol (132360-48-6)

Guidance literature:

With N-iodo-succinimide; In acetonitrile; at 100 ℃; for 0.416667h; microwave irradiation;

DOI:10.1016/j.tetlet.2003.09.206

upstream raw materials:

ethyl 2-O-benzoyl-3,4,6-tri-O-benzyl-1-thio-α-D-mannopyranoside

3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-D(L)-myo-inositol

1D-3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-myo-inositol

3,4,6-tri-O-benzyl-β-D-mannopyranose 1,2-(pent-4-enyl orthobenzoate)

Downstream raw materials:

3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-6-O-(3',4',6'-tri-O-benzyl-α-D-mannopyranosyl)-L-myo-inositol

3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-6-O-(3',4',6'-tri-O-benzyl-α-D-mannopyranosyl)-D-myo-inositol

C₆₁H₆₅F₃O₁₃S

3,4,5-tri-O-benzyl-6-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-D-myo-inositol