Technology Process of 2-(3,5-Dibrom-2-hydroxyphenyl)-1-methylpyrrol
There total 10 articles about 2-(3,5-Dibrom-2-hydroxyphenyl)-1-methylpyrrol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
boron tribromide;
In
hexane; dichloromethane;
1.) - 78 deg C up to room temperature, 4 h; 2.) room temperature, 1 h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: thionyl chloride / 1 h / Heating
2: 1.) Mg
3: 1.) glacial acetic acid, conc. HCl; 2.) glacial acetic acid, conc. HCl / 1.) water, 3 d, RT; 2.) water, 3 d, RT
4: 87 percent / ethanol / 3 h / Heating
5: 90 percent / 1M BBr3 / CH2Cl2; hexane / 1.) - 78 deg C up to room temperature, 4 h; 2.) room temperature, 1 h
With
hydrogenchloride; thionyl chloride; boron tribromide; magnesium; acetic acid;
In
ethanol; hexane; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 96 percent / KOH / methanol; H2O / 4 h / Heating
2: thionyl chloride / 1 h / Heating
3: 1.) Mg
4: 1.) glacial acetic acid, conc. HCl; 2.) glacial acetic acid, conc. HCl / 1.) water, 3 d, RT; 2.) water, 3 d, RT
5: 87 percent / ethanol / 3 h / Heating
6: 90 percent / 1M BBr3 / CH2Cl2; hexane / 1.) - 78 deg C up to room temperature, 4 h; 2.) room temperature, 1 h
With
hydrogenchloride; potassium hydroxide; thionyl chloride; boron tribromide; magnesium; acetic acid;
In
methanol; ethanol; hexane; dichloromethane; water;
