3,5-DIBROMO-2-METHOXYBENZOIC ACID

Base Information

• Chemical Name: 3,5-DIBROMO-2-METHOXYBENZOIC ACID
• CAS No.: 13130-23-9
• Molecular Formula: C8H6Br2O3
• Molecular Weight: 309.942
• Hs Code.: 2918990090
• Mol file: 13130-23-9.mol

Synonyms:o-Anisicacid, 3,5-dibromo- (6CI,7CI,8CI);3,5-Dibromo-2-methoxybenzoic acid;

Chemical Property of 3,5-DIBROMO-2-METHOXYBENZOIC ACID

Chemical Property:

• Vapor Pressure: 3.1E-06mmHg at 25°C
• Melting Point: 198-200 °C
• Refractive Index: 1.614
• Boiling Point: 373.326 °C at 760 mmHg
• Flash Point: 179.581 °C
• PSA: 46.53000
• Density: 1.957 g/cm³
• LogP: 2.91840
• Storage Temp.: 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

3,5-Dibromo-2-methoxybenzoicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,5-DIBROMO-2-METHOXYBENZOIC ACID

There total 20 articles about 3,5-DIBROMO-2-METHOXYBENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

3,5-dibromo-2-methoxy-benzoic acid methyl ester (15790-59-7) → 3,5-dibromo-2-methoxybenzoic acid (13130-23-9)

Guidance literature:

With potassium hydroxide; In methanol; water; for 4h; Heating;

Reference yield: 94.0%

3,5-dibromosalicylic acid (3147-55-5) + methyl iodide (74-88-4) → 3,5-dibromo-2-methoxybenzoic acid (13130-23-9)

Guidance literature:

With potassium carbonate; at 20 - 80 ℃;

Reference yield: 93.0%

3,5-dibromo-2-methoxybenzaldehyde (61657-65-6) → 3,5-dibromo-2-methoxybenzoic acid (13130-23-9)

Guidance literature:

With sodium hydroxide; dihydrogen peroxide; In methanol; for 15h; Heating;

DOI:10.1007/BF02494298

upstream raw materials:

2,4,6-tribromoanisole

1-(3,5-dibromo-2-methoxy-phenyl)-ethanone

3,5-dibromosalicylic acid

dimethyl sulfate

Downstream raw materials:

3,5-dibromo-2-methoxy-benzoic acid ethyl ester

3,5-dibromo-2-hydroxy-N-phenylbenzamide

3,5-dibromo-2-methoxy-N-(1-benzyl-4-piperidinyl)benzamide

2,7,12-Tris-(3,5-dibrom-2-methoxyphenyl)-4,4a,9,9a,14,14a-hexahydro-3H,8H,13H-tripyradizino<1,6-a:1',6'-c:1',6'-e>-s-triazin

Refernces

• 1、 -. "COMPOUNDS AND METHODS OF INHIBITING BACTERIAL CHAPERONIN SYSTEMS". Paragraph 0208; 0209. . Retrieved 2020/05/28.
• 2、 -. "A cyclotrimethoxone-substituted salicylate compound and anti-tumor effect thereof". Paragraph 0041-0043. . Retrieved 2017/07/19.