3-{[1-p-Tolyl-meth-(E)-ylidene]-amino}-1H-indole-2-carboxylic acid [1-p-tolyl-meth-(E)-ylidene]-hydrazide

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Chemical Name:3-{[1-p-Tolyl-meth-(E)-ylidene]-amino}-1H-indole-2-carboxylic acid [1-p-tolyl-meth-(E)-ylidene]-hydrazide
CAS No.:143603-96-7
Molecular Formula:C₂₅H₂₂N₄O
Molecular Weight:394.476
Hs Code.:

Synonyms:3-{[1-p-Tolyl-meth-(E)-ylidene]-amino}-1H-indole-2-carboxylic acid [1-p-tolyl-meth-(E)-ylidene]-hydrazide

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Chemical Property of 3-{[1-p-Tolyl-meth-(E)-ylidene]-amino}-1H-indole-2-carboxylic acid [1-p-tolyl-meth-(E)-ylidene]-hydrazide

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Technology Process of 3-{[1-p-Tolyl-meth-(E)-ylidene]-amino}-1H-indole-2-carboxylic acid [1-p-tolyl-meth-(E)-ylidene]-hydrazide

There total 2 articles about 3-{[1-p-Tolyl-meth-(E)-ylidene]-amino}-1H-indole-2-carboxylic acid [1-p-tolyl-meth-(E)-ylidene]-hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 104-87-0
4-methyl-benzaldehyde

: 110963-29-6
3-Aminoindole-2-carbohydrazide

: 143603-96-7
3-{[1-p-Tolyl-meth-(E)-ylidene]-amino}-1H-indole-2-carboxylic acid [1-p-tolyl-meth-(E)-ylidene]-hydrazide

Guidance literature:: With hydrogenchloride; In ethanol; for 1h; Heating;
DOI:10.1002/ardp.19923250712

Reference yield:

: 87223-77-6
ethyl 3-amino-1H-indole-2-carboxylate

: 143603-96-7
3-{[1-p-Tolyl-meth-(E)-ylidene]-amino}-1H-indole-2-carboxylic acid [1-p-tolyl-meth-(E)-ylidene]-hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / hydrazine hydrate / 4 h / Heating

2: 80 percent / 25percent HCl / ethanol / 1 h / Heating

With hydrogenchloride; hydrazine hydrate; In ethanol;
DOI:10.1002/ardp.19923250712