Butanoicacid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo-, phenylmethyl ester, (2S)-

Base Information Edit

Chemical Name:Butanoicacid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo-, phenylmethyl ester, (2S)-
CAS No.:124994-66-7
Molecular Formula:C16H21 N O5
Molecular Weight:307.346
Hs Code.:
Mol file:124994-66-7.mol

Synonyms:Butanoicacid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo-, phenylmethyl ester, (S)-;(S)-2-[(tert-Butoxycarbonyl)amino]-4-oxobutanoic acid benzyl ester

Suppliers and Price of Butanoicacid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo-, phenylmethyl ester, (2S)-

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Butanoicacid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo-, phenylmethyl ester, (2S)- Edit

Chemical Property:

PSA：85.19000
LogP:2.41650

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Butanoicacid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo-, phenylmethyl ester, (2S)-

There total 19 articles about Butanoicacid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo-, phenylmethyl ester, (2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 105183-60-6
(S)-benzyl 2-((tert-butoxycarbonyl)amino)-4-hydroxybutanoate

: 124994-66-7
(S)-benzyl-4-oxo-2-<<(1,1-dimethylethoxy)carbonyl>amino>butanoate

Guidance literature:: (S)-benzyl 2-((tert-butoxycarbonyl)amino)-4-hydroxybutanoate; With oxalyl dichloride; In dichloromethane; dimethyl sulfoxide; at -78 ℃; for 1.08333h;

With triethylamine; In dichloromethane; dimethyl sulfoxide; at 20 ℃; for 1h;

Reference yield: 95.0%

: 1079307-01-9
(S)-benzyl 2-(tert-butoxycarbonylamino)-4-(methoxy(methyl)amino)-4-oxobutanoate

: 124994-66-7
(S)-benzyl-4-oxo-2-<<(1,1-dimethylethoxy)carbonyl>amino>butanoate

Guidance literature:: With diisobutylaluminium hydride; In tetrahydrofuran; at -60 ℃; for 0.5h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.1c00296

Reference yield: 60.0%

: 30925-18-9
2-tert-butoxycarbonylamino-succinic acid 1-benzyl ester

: 124994-66-7
(S)-benzyl-4-oxo-2-<<(1,1-dimethylethoxy)carbonyl>amino>butanoate

Guidance literature:: 2-tert-butoxycarbonylamino-succinic acid 1-benzyl ester; With pyridine; oxalyl dichloride; N,N-dimethyl-formamide; In tetrahydrofuran; acetonitrile; at -30 ℃; for 1h; Inert atmosphere;

With lithium tri-t-butoxyaluminum hydride; In tetrahydrofuran; acetonitrile; at -78 ℃; for 0.5h; Inert atmosphere;
DOI:10.1007/s00726-012-1349-0