Phosphoric acid dibenzyl ester 4-[(Z)-2-(3,5-dimethoxy-phenyl)-vinyl]-phenyl ester

Base Information

Chemical Name:Phosphoric acid dibenzyl ester 4-[(Z)-2-(3,5-dimethoxy-phenyl)-vinyl]-phenyl ester
CAS No.:441351-38-8
Molecular Formula:C₃₀H₂₉O₆P
Molecular Weight:516.53
Hs Code.:

Synonyms:Phosphoric acid dibenzyl ester 4-[(Z)-2-(3,5-dimethoxy-phenyl)-vinyl]-phenyl ester

Suppliers and Price of Phosphoric acid dibenzyl ester 4-[(Z)-2-(3,5-dimethoxy-phenyl)-vinyl]-phenyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Phosphoric acid dibenzyl ester 4-[(Z)-2-(3,5-dimethoxy-phenyl)-vinyl]-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Phosphoric acid dibenzyl ester 4-[(Z)-2-(3,5-dimethoxy-phenyl)-vinyl]-phenyl ester

There total 6 articles about Phosphoric acid dibenzyl ester 4-[(Z)-2-(3,5-dimethoxy-phenyl)-vinyl]-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 17176-77-1
Dibenzyl phosphite

: 441351-32-2
(Z)-4-hydroxy-3',5'-dimethoxystilbene

: 441351-38-8
Phosphoric acid dibenzyl ester 4-[(Z)-2-(3,5-dimethoxy-phenyl)-vinyl]-phenyl ester

Guidance literature:: (Z)-4-hydroxy-3',5'-dimethoxystilbene; With dmap; N-ethyl-N,N-diisopropylamine; In tetrachloromethane; acetonitrile; at -10 ℃; for 0.5h;

Dibenzyl phosphite; In tetrachloromethane; acetonitrile; for 12h; Further stages.;
DOI:10.1021/jm010119y

Reference yield:

: 705-76-0
3,5-dimethoxybenzyl alcohol

: 441351-38-8
Phosphoric acid dibenzyl ester 4-[(Z)-2-(3,5-dimethoxy-phenyl)-vinyl]-phenyl ester

Guidance literature:: Multi-step reaction with 5 steps

1.1: 89 percent / PBr₃ / CH₂Cl₂ / 12 h / 0 °C

2.1: 92 percent / toluene / 12 h / Heating

3.1: n-BuLi / tetrahydrofuran / -78 °C

3.2: tetrahydrofuran

4.1: 88 percent / Bu₄NF / tetrahydrofuran / 0.75 h

5.1: N,N-(dimethylamino)pyridine; DIEA / acetonitrile; CCl₄ / 0.5 h / -10 °C

5.2: 85 percent / acetonitrile; CCl₄ / 12 h

With dmap; n-butyllithium; tetrabutyl ammonium fluoride; phosphorus tribromide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; tetrachloromethane; dichloromethane; toluene; acetonitrile; 3.2: Wittig reaction;
DOI:10.1021/jm010119y

Reference yield:

: 7311-34-4
3,5-dimethoxybenzaldehdye

: 441351-38-8
Phosphoric acid dibenzyl ester 4-[(Z)-2-(3,5-dimethoxy-phenyl)-vinyl]-phenyl ester

Guidance literature:: Multi-step reaction with 6 steps

1.1: 93 percent / NaBH₄ / methanol / 0 °C

2.1: 89 percent / PBr₃ / CH₂Cl₂ / 12 h / 0 °C

3.1: 92 percent / toluene / 12 h / Heating

4.1: n-BuLi / tetrahydrofuran / -78 °C

4.2: tetrahydrofuran

5.1: 88 percent / Bu₄NF / tetrahydrofuran / 0.75 h

6.1: N,N-(dimethylamino)pyridine; DIEA / acetonitrile; CCl₄ / 0.5 h / -10 °C

6.2: 85 percent / acetonitrile; CCl₄ / 12 h

With dmap; sodium tetrahydroborate; n-butyllithium; tetrabutyl ammonium fluoride; phosphorus tribromide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; tetrachloromethane; dichloromethane; toluene; acetonitrile; 4.2: Wittig reaction;
DOI:10.1021/jm010119y