2-(3'-chloro-5'-methylidenecyclohex-3'-enyl)ethan-1-yl diphenylmethylsilyl ether

Base Information

Chemical Name:2-(3'-chloro-5'-methylidenecyclohex-3'-enyl)ethan-1-yl diphenylmethylsilyl ether
CAS No.:1393581-14-0
Molecular Formula:C₂₂H₂₅ClOSi
Molecular Weight:368.978
Hs Code.:

Synonyms:2-(3'-chloro-5'-methylidenecyclohex-3'-enyl)ethan-1-yl diphenylmethylsilyl ether

Suppliers and Price of 2-(3'-chloro-5'-methylidenecyclohex-3'-enyl)ethan-1-yl diphenylmethylsilyl ether

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(3'-chloro-5'-methylidenecyclohex-3'-enyl)ethan-1-yl diphenylmethylsilyl ether

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(3'-chloro-5'-methylidenecyclohex-3'-enyl)ethan-1-yl diphenylmethylsilyl ether

There total 3 articles about 2-(3'-chloro-5'-methylidenecyclohex-3'-enyl)ethan-1-yl diphenylmethylsilyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1393581-13-9
5-[2'-(diphenylmethylsilyloxyethyl)]-3-chloro-2-cyclohexen-1-one

: 1779-49-3
Methyltriphenylphosphonium bromide

: 1393581-14-0
2-(3'-chloro-5'-methylidenecyclohex-3'-enyl)ethan-1-yl diphenylmethylsilyl ether

Guidance literature:: Methyltriphenylphosphonium bromide; With potassium 2-methylbutan-2-olate; In benzene; for 1h; Reflux;

5-[2'-(diphenylmethylsilyloxyethyl)]-3-chloro-2-cyclohexen-1-one; In benzene; at 20 ℃; for 0.5h;
DOI:10.1016/j.tet.2012.05.084

Reference yield:

: C₈H₁₁ClO₂

: 1393581-14-0
2-(3'-chloro-5'-methylidenecyclohex-3'-enyl)ethan-1-yl diphenylmethylsilyl ether

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1H-imidazole / N,N-dimethyl-formamide / 0.5 h / 20 °C

2.1: potassium 2-methylbutan-2-olate / benzene / 1 h / Reflux

2.2: 0.5 h / 20 °C

With 1H-imidazole; potassium 2-methylbutan-2-olate; In N,N-dimethyl-formamide; benzene;
DOI:10.1016/j.tet.2012.05.084

Reference yield:

: 43152-25-6
C₈H₁₀O₄

: 1393581-14-0
2-(3'-chloro-5'-methylidenecyclohex-3'-enyl)ethan-1-yl diphenylmethylsilyl ether

Guidance literature:: Multi-step reaction with 4 steps

1.1: oxalyl dichloride / 0.5 h / Reflux

2.1: lithium tris[(3-ethyl-3-pentyl)oxy]aluminohydride / tetrahydrofuran / 4.5 h / -78 °C

2.2: -78 °C / Saturated solution

3.1: 1H-imidazole / N,N-dimethyl-formamide / 0.5 h / 20 °C

4.1: potassium 2-methylbutan-2-olate / benzene / 1 h / Reflux

4.2: 0.5 h / 20 °C

With 1H-imidazole; oxalyl dichloride; lithium tris[(3-ethyl-3-pentyl)oxy]aluminohydride; potassium 2-methylbutan-2-olate; In tetrahydrofuran; N,N-dimethyl-formamide; benzene;
DOI:10.1016/j.tet.2012.05.084