[(R)-2-Benzyloxy-1-(6-methoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-(2,2-diethoxy-ethyl)-amine

Base Information

Chemical Name:[(R)-2-Benzyloxy-1-(6-methoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-(2,2-diethoxy-ethyl)-amine
CAS No.:351377-76-9
Molecular Formula:C₂₄H₃₃NO₆
Molecular Weight:431.529
Hs Code.:

Synonyms:[(R)-2-Benzyloxy-1-(6-methoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-(2,2-diethoxy-ethyl)-amine

Suppliers and Price of [(R)-2-Benzyloxy-1-(6-methoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-(2,2-diethoxy-ethyl)-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [(R)-2-Benzyloxy-1-(6-methoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-(2,2-diethoxy-ethyl)-amine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [(R)-2-Benzyloxy-1-(6-methoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-(2,2-diethoxy-ethyl)-amine

There total 9 articles about [(R)-2-Benzyloxy-1-(6-methoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-(2,2-diethoxy-ethyl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (R)-2-Azido-2-(6-methoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethanol

: 351377-76-9
[(R)-2-Benzyloxy-1-(6-methoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-(2,2-diethoxy-ethyl)-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 2.1 g / NaH; n-Bu₄NI / tetrahydrofuran / 12 h / 20 °C

2: H₂ / Pd/C / ethyl acetate / 5 h / 760.05 Torr

3: 1.7 g / K₂CO₃ / acetonitrile / 72 h / Heating

With hydrogen; tetra-(n-butyl)ammonium iodide; sodium hydride; potassium carbonate; palladium on activated charcoal; In tetrahydrofuran; ethyl acetate; acetonitrile;
DOI:10.1021/ol016844k

Reference yield:

: 7-((R)-1-Azido-2-benzyloxy-ethyl)-5-methoxy-4-methyl-benzo[1,3]dioxole

: 351377-76-9
[(R)-2-Benzyloxy-1-(6-methoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-(2,2-diethoxy-ethyl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd/C / ethyl acetate / 5 h / 760.05 Torr

2: 1.7 g / K₂CO₃ / acetonitrile / 72 h / Heating

With hydrogen; potassium carbonate; palladium on activated charcoal; In ethyl acetate; acetonitrile;
DOI:10.1021/ol016844k

Reference yield:

: 7149-92-0
2,4-dimethoxy-3-methylbenzaldehyde

: 351377-76-9
[(R)-2-Benzyloxy-1-(6-methoxy-7-methyl-benzo[1,3]dioxol-4-yl)-ethyl]-(2,2-diethoxy-ethyl)-amine

Guidance literature:: Multi-step reaction with 9 steps

1.1: m-CPBA; p-TsOH / CH₂Cl₂ / 7 h / 20 °C

1.2: 99 percent / K₂CO₃ / CH₂Cl₂; methanol / 4 h / 20 °C

2.1: 81 percent / Br₂; K₂CO₃ / CH₂Cl₂ / 2 h / -78 °C

3.1: 74 percent / AlCl₃ / CH₂Cl₂ / 12 h / 20 °C

4.1: 80 percent / Cs₂CO₃ / acetonitrile / 4 h / Heating

5.1: 90 percent / Pd(PPh₃)4 / toluene / 9 h / Heating

6.1: 2.1 g / NaH; n-Bu₄NI / tetrahydrofuran / 12 h / 20 °C

7.1: H₂ / Pd/C / ethyl acetate / 5 h / 760.05 Torr

8.1: 1.7 g / K₂CO₃ / acetonitrile / 72 h / Heating

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; aluminium trichloride; hydrogen; bromine; tetra-(n-butyl)ammonium iodide; sodium hydride; potassium carbonate; caesium carbonate; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; ethyl acetate; toluene; acetonitrile;
DOI:10.1021/ol016844k