Phenol, 2,4-dimethoxy-3-methyl-

Base Information

• Chemical Name: Phenol, 2,4-dimethoxy-3-methyl-
• CAS No.: 19676-67-6
• Molecular Formula: C9H12O3
• Molecular Weight: 168.192
• DSSTox Substance ID: DTXSID80450382
• Nikkaji Number: J1.504.303B
• Wikidata: Q82270070
• Mol file: 19676-67-6.mol

Synonyms:2,4-dimethoxy-3-methylphenol;Phenol, 2,4-dimethoxy-3-methyl-;19676-67-6;2,4-dimethoxy-3-methyl-phenol;SCHEMBL5141870;DTXSID80450382;FMFMDOJFLHYBOM-UHFFFAOYSA-N;FT-0734496

Chemical Property of Phenol, 2,4-dimethoxy-3-methyl-

Chemical Property:

• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 168.078644241
• Heavy Atom Count: 12
• Complexity: 138

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=CC(=C1OC)O)OC

Technology Process of Phenol, 2,4-dimethoxy-3-methyl-

There total 12 articles about Phenol, 2,4-dimethoxy-3-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,4-dimethoxy-3-methylbenzaldehyde (7149-92-0) → 2,4-dimethoxy-3-methylphenol (19676-67-6)

Guidance literature:

2,4-dimethoxy-3-methylbenzaldehyde; With selenium(IV) oxide; dihydrogen peroxide; In water; tert-butyl alcohol; at 50 ℃; for 1.5h;

With potassium carbonate; In methanol; for 4h;

DOI:10.1002/chem.201202073

Reference yield: 98.0%

acetic acid 2,4-dimethoxy-3-methyl-phenyl ester (96502-90-8) → 2,4-dimethoxy-3-methylphenol (19676-67-6)

Guidance literature:

With potassium hydroxide; In methanol; for 3h; Heating;

DOI:10.1055/s-2002-33919

Reference yield: 85.0%

2,6-dimethoxytoluene (5673-07-4) → 2,4-dimethoxy-3-methylphenol (19676-67-6)

Guidance literature:

With dihydrogen peroxide; trifluoroacetic acid; In acetonitrile; at 75 ℃; for 2h;

DOI:10.1002/ejoc.201800359

upstream raw materials:

2,4-dimethoxy-3-methylbenzaldehyde

2,4-dimethoxy-3-methylbenzoic acid

acetic acid 2,4-dimethoxy-3-methyl-phenyl ester

2′,4′-dimethoxy-3′-methylacetophenone

Downstream raw materials:

2,3,6-trimethoxytoluene

2,4-dimethoxy-3-methylphenyl 2,4-pentadienyl ether

<1,1-(2)H2>-2,4-pentadienyl 2,4-dimethoxy-3-methylphenyl ether

[(Z)-6-Benzyloxy-4-bromo-3-(2,4-dimethoxy-3-methyl-phenoxy)-hex-4-enyloxy]-tert-butyl-dimethyl-silane