4(S)-(1-methylethyl)-3-[1-oxo-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propyl]-2-oxazolidinone

Base Information

Chemical Name:4(S)-(1-methylethyl)-3-[1-oxo-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propyl]-2-oxazolidinone
CAS No.:160447-11-0
Molecular Formula:C₃₁H₃₁N₃O₃
Molecular Weight:493.605
Hs Code.:

Synonyms:4(S)-(1-methylethyl)-3-[1-oxo-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propyl]-2-oxazolidinone

Suppliers and Price of 4(S)-(1-methylethyl)-3-[1-oxo-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propyl]-2-oxazolidinone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4(S)-(1-methylethyl)-3-[1-oxo-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propyl]-2-oxazolidinone

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 4(S)-(1-methylethyl)-3-[1-oxo-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propyl]-2-oxazolidinone

There total 6 articles about 4(S)-(1-methylethyl)-3-[1-oxo-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propyl]-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 17016-83-0
(4S)-4-isopropyl-1,3-oxazolidin-2-one

: C₃₀H₃₀N₂O₃

: 160447-11-0
4(S)-(1-methylethyl)-3-[1-oxo-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propyl]-2-oxazolidinone

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 0 ℃; for 1.58333h;
DOI:10.1016/S0968-0896(98)80011-4

Reference yield: 84.0%

: 160447-11-0
4(S)-(1-methylethyl)-3-[1-oxo-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propyl]-2-oxazolidinone

Guidance literature:

Reference yield:

: 76-83-5
trityl chloride

: 160447-11-0
4(S)-(1-methylethyl)-3-[1-oxo-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propyl]-2-oxazolidinone

Guidance literature:: Multi-step reaction with 4 steps

1: Et₃N / CH₂Cl₂ / 63 h / 25 °C

2: 77.14 g / LiOH*H₂O / tetrahydrofuran; H₂O / 3 h / 25 °C

3: Et₃N / tetrahydrofuran / 1.25 h / -78 - 0 °C

4: 84 percent / n-BuLi / tetrahydrofuran; hexane / 1.58 h / -78 - 0 °C

With lithium hydroxide; n-butyllithium; triethylamine; In tetrahydrofuran; hexane; dichloromethane; water; 1: Alkylation / 2: Hydrolysis / 3: Acylation / 4: Acylation;
DOI:10.1016/S0968-0896(98)80011-4