Technology Process of C18H22BrN3O2
There total 8 articles about C18H22BrN3O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
ammonium acetate;
In
xylene;
at 140 ℃;
Sealed tube;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: dmap; triethylamine / dichloromethane / 18 h / 24 °C
2.1: lithium borohydride / tetrahydrofuran; toluene / 1.08 h / -50 - -45 °C
2.2: -50 - 20 °C
3.1: diethylzinc / toluene / -30 - -21 °C
4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C
5.1: sodium periodate / ruthenium trichloride / tetrachloromethane; water; acetonitrile / 1.25 h
6.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 20 °C
7.1: ammonium acetate / xylene / 140 °C / Sealed tube; Inert atmosphere
With
dmap; sodium periodate; lithium borohydride; ammonium acetate; tetrabutyl ammonium fluoride; diethylzinc; triethylamine; N-ethyl-N,N-diisopropylamine;
ruthenium trichloride;
In
tetrahydrofuran; tetrachloromethane; dichloromethane; water; toluene; acetonitrile; xylene;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C
2: sodium periodate / ruthenium trichloride / tetrachloromethane; water; acetonitrile / 1.25 h
3: N-ethyl-N,N-diisopropylamine / acetonitrile / 20 °C
4: ammonium acetate / xylene / 140 °C / Sealed tube; Inert atmosphere
With
sodium periodate; ammonium acetate; tetrabutyl ammonium fluoride; N-ethyl-N,N-diisopropylamine;
ruthenium trichloride;
In
tetrahydrofuran; tetrachloromethane; water; acetonitrile; xylene;