(S)-methyl 3-(2-(3-(5-methyl-2-phenyloxazol-4-yl)propyl)benzo[d]oxazol-5-yl)-2-phenoxypropanoate

Base Information

Chemical Name:(S)-methyl 3-(2-(3-(5-methyl-2-phenyloxazol-4-yl)propyl)benzo[d]oxazol-5-yl)-2-phenoxypropanoate
CAS No.:1334871-98-5
Molecular Formula:C₃₀H₂₈N₂O₅
Molecular Weight:496.563
Hs Code.:

Synonyms:(S)-methyl 3-(2-(3-(5-methyl-2-phenyloxazol-4-yl)propyl)benzo[d]oxazol-5-yl)-2-phenoxypropanoate

Suppliers and Price of (S)-methyl 3-(2-(3-(5-methyl-2-phenyloxazol-4-yl)propyl)benzo[d]oxazol-5-yl)-2-phenoxypropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-methyl 3-(2-(3-(5-methyl-2-phenyloxazol-4-yl)propyl)benzo[d]oxazol-5-yl)-2-phenoxypropanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-methyl 3-(2-(3-(5-methyl-2-phenyloxazol-4-yl)propyl)benzo[d]oxazol-5-yl)-2-phenoxypropanoate

There total 19 articles about (S)-methyl 3-(2-(3-(5-methyl-2-phenyloxazol-4-yl)propyl)benzo[d]oxazol-5-yl)-2-phenoxypropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 1262547-46-5
(S)-methyl 2-hydroxy-3-(2-(3-(5-methyl-2-phenyloxazol-4-yl)propyl)benzo[d]oxazol-5-yl)propanoate

: 108-95-2,27073-41-2
phenol

: 1334871-98-5
(S)-methyl 3-(2-(3-(5-methyl-2-phenyloxazol-4-yl)propyl)benzo[d]oxazol-5-yl)-2-phenoxypropanoate

Guidance literature:: With di-isopropyl azodicarboxylate; triphenylphosphine; In toluene; at 0 - 20 ℃; for 12h;
DOI:10.1016/j.ejmech.2011.05.028

Reference yield:

: 501031-61-4
2-(5-methyl-2-phenyloxazol-4-yl)acetaldehyde

: 1334871-98-5
(S)-methyl 3-(2-(3-(5-methyl-2-phenyloxazol-4-yl)propyl)benzo[d]oxazol-5-yl)-2-phenoxypropanoate

Guidance literature:: Multi-step reaction with 8 steps

1.1: potassium tert-butylate / tetrahydrofuran / 1 h / -10 °C

1.2: 0.17 h / -10 °C

2.1: platinum(IV) oxide trihydrate; hydrogen / methanol / 12 h / 760.05 Torr

3.1: lithium hydroxide monohydrate / ethanol / 1 h / 20 °C

3.2: pH 3

4.1: triethylamine / tetrahydrofuran / 0.5 h / -78 - 0 °C

5.1: n-butyllithium / tetrahydrofuran; hexane

5.2: 0.5 h / -78 - 20 °C

6.1: potassium hexamethylsilazane / tetrahydrofuran / 1 h / -78 °C

6.2: 4 h / -78 °C

7.1: ethylmagnesium bromide / diethyl ether / 0.17 h / -10 °C

8.1: di-isopropyl azodicarboxylate; triphenylphosphine / toluene / 12 h / 0 - 20 °C

With n-butyllithium; lithium hydroxide monohydrate; platinum(IV) oxide trihydrate; di-isopropyl azodicarboxylate; ethylmagnesium bromide; potassium tert-butylate; hydrogen; potassium hexamethylsilazane; triethylamine; triphenylphosphine; In tetrahydrofuran; methanol; diethyl ether; ethanol; hexane; toluene; 1.2: Horner-Wadsworth-Emmons olefination / 6.2: Davis asymmetric oxidation / 8.1: Mitsunobu reaction;
DOI:10.1016/j.ejmech.2011.05.028

Reference yield:

: 1262547-37-4
methyl 3-(2-(chloromethyl)benzo[d]oxazol-5-yl)propanoate

: 1334871-98-5
(S)-methyl 3-(2-(3-(5-methyl-2-phenyloxazol-4-yl)propyl)benzo[d]oxazol-5-yl)-2-phenoxypropanoate

Guidance literature:: Multi-step reaction with 9 steps

1.1: N,N-dimethyl-formamide / 3 h / 150 °C

2.1: potassium tert-butylate / tetrahydrofuran / 1 h / -10 °C

2.2: 0.17 h / -10 °C

3.1: platinum(IV) oxide trihydrate; hydrogen / methanol / 12 h / 760.05 Torr

4.1: lithium hydroxide monohydrate / ethanol / 1 h / 20 °C

4.2: pH 3

5.1: triethylamine / tetrahydrofuran / 0.5 h / -78 - 0 °C

6.1: n-butyllithium / tetrahydrofuran; hexane

6.2: 0.5 h / -78 - 20 °C

7.1: potassium hexamethylsilazane / tetrahydrofuran / 1 h / -78 °C

7.2: 4 h / -78 °C

8.1: ethylmagnesium bromide / diethyl ether / 0.17 h / -10 °C

9.1: di-isopropyl azodicarboxylate; triphenylphosphine / toluene / 12 h / 0 - 20 °C

With n-butyllithium; lithium hydroxide monohydrate; platinum(IV) oxide trihydrate; di-isopropyl azodicarboxylate; ethylmagnesium bromide; potassium tert-butylate; hydrogen; potassium hexamethylsilazane; triethylamine; triphenylphosphine; In tetrahydrofuran; methanol; diethyl ether; ethanol; hexane; N,N-dimethyl-formamide; toluene; 2.2: Horner-Wadsworth-Emmons olefination / 7.2: Davis asymmetric oxidation / 9.1: Mitsunobu reaction;
DOI:10.1016/j.ejmech.2011.05.028