6-methoxy-3-[[1-(2-methoxyethyl)-1H-tetrazol-5-yl][(2-phenylethyl)(phenylmethyl)-amino]methyl]-2(1H)-quinolinone

Base Information

Chemical Name:6-methoxy-3-[[1-(2-methoxyethyl)-1H-tetrazol-5-yl][(2-phenylethyl)(phenylmethyl)-amino]methyl]-2(1H)-quinolinone
CAS No.:570365-12-7
Molecular Formula:C₃₀H₃₂N₆O₃
Molecular Weight:524.622
Hs Code.:

Synonyms:6-methoxy-3-[[1-(2-methoxyethyl)-1H-tetrazol-5-yl][(2-phenylethyl)(phenylmethyl)-amino]methyl]-2(1H)-quinolinone

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Chemical Property of 6-methoxy-3-[[1-(2-methoxyethyl)-1H-tetrazol-5-yl][(2-phenylethyl)(phenylmethyl)-amino]methyl]-2(1H)-quinolinone

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Technology Process of 6-methoxy-3-[[1-(2-methoxyethyl)-1H-tetrazol-5-yl][(2-phenylethyl)(phenylmethyl)-amino]methyl]-2(1H)-quinolinone

There total 3 articles about 6-methoxy-3-[[1-(2-methoxyethyl)-1H-tetrazol-5-yl][(2-phenylethyl)(phenylmethyl)-amino]methyl]-2(1H)-quinolinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 758640-21-0,103-32-2
N-Benzylaniline

: 43219-50-7
2-methoxyethyl isocyanide

: 123990-78-3
6-methoxy-2-oxo-1,2-dihydroquinolin-3-carboxaldehyde

: 570365-12-7
6-methoxy-3-[[1-(2-methoxyethyl)-1H-tetrazol-5-yl][(2-phenylethyl)(phenylmethyl)-amino]methyl]-2(1H)-quinolinone

Guidance literature:: N-Benzylaniline; 6-methoxy-2-oxo-1,2-dihydroquinolin-3-carboxaldehyde; In methanol; at 50 ℃;

2-methoxyethyl isocyanide; With trimethylsilylazide; In methanol; at 50 ℃; for 10h;

Reference yield: 35.0%

: 3647-71-0
N-benzyl-2-phenylethylamine

: 43219-50-7
2-methoxyethyl isocyanide

: 123990-78-3
6-methoxy-2-oxo-1,2-dihydroquinolin-3-carboxaldehyde

: 570365-12-7
6-methoxy-3-[[1-(2-methoxyethyl)-1H-tetrazol-5-yl][(2-phenylethyl)(phenylmethyl)-amino]methyl]-2(1H)-quinolinone

Guidance literature:: N-benzyl-2-phenylethylamine; 6-methoxy-2-oxo-1,2-dihydroquinolin-3-carboxaldehyde; In methanol; at 50 ℃;

2-methoxyethyl isocyanide; With trimethylsilylazide; In methanol; at 50 ℃; for 10h;

Reference yield:

: 73568-29-3
2-chloro-6-methoxyquinolin-3-carboxaldehyde

: 570365-12-7
6-methoxy-3-[[1-(2-methoxyethyl)-1H-tetrazol-5-yl][(2-phenylethyl)(phenylmethyl)-amino]methyl]-2(1H)-quinolinone

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic acid / water / 8 h / Reflux

2.1: methanol / 50 °C

2.2: 10 h / 50 °C

With acetic acid; In methanol; water;