(2E,4E)-(6R,7S)-7-Benzyloxy-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,4,6-trimethyl-hepta-2,4-dienal

Base Information

Chemical Name:(2E,4E)-(6R,7S)-7-Benzyloxy-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,4,6-trimethyl-hepta-2,4-dienal
CAS No.:596095-58-8
Molecular Formula:C₂₂H₃₀O₄
Molecular Weight:358.478
Hs Code.:

Synonyms:(2E,4E)-(6R,7S)-7-Benzyloxy-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,4,6-trimethyl-hepta-2,4-dienal

Suppliers and Price of (2E,4E)-(6R,7S)-7-Benzyloxy-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,4,6-trimethyl-hepta-2,4-dienal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2E,4E)-(6R,7S)-7-Benzyloxy-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,4,6-trimethyl-hepta-2,4-dienal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2E,4E)-(6R,7S)-7-Benzyloxy-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,4,6-trimethyl-hepta-2,4-dienal

There total 10 articles about (2E,4E)-(6R,7S)-7-Benzyloxy-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,4,6-trimethyl-hepta-2,4-dienal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 596095-57-7
(2E,4E)-(6R,7S)-7-Benzyloxy-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,4,6-trimethyl-hepta-2,4-dien-1-ol

: 596095-58-8
(2E,4E)-(6R,7S)-7-Benzyloxy-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,4,6-trimethyl-hepta-2,4-dienal

Guidance literature:: With phthalic acid dimethyl ester; In dichloromethane; at 0 ℃;
DOI:10.1016/S0040-4039(03)01173-0

Reference yield:

: 88406-01-3
2,3-O-isopropylidene-1-C-<(1R)-1-methylprop-2-enyl>-D-erythro-glycerol

: 596095-58-8
(2E,4E)-(6R,7S)-7-Benzyloxy-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,4,6-trimethyl-hepta-2,4-dienal

Guidance literature:: Multi-step reaction with 8 steps

1.1: 66 percent / NaH; TBAI / dimethylformamide / 20 °C

2.1: O₃ / CH₂Cl₂ / -78 °C

2.2: 80 percent / PPh₃ / -25 °C

3.1: 70 percent / n-BuLi / tetrahydrofuran / -78 - 20 °C

4.1: 94 percent / DIBAL-H / hexane / -78 °C

5.1: 85 percent / DMP / CH₂Cl₂ / 0 °C

6.1: 65 percent / n-BuLi / tetrahydrofuran / -78 - 20 °C

7.1: 88 percent / DIBAL-H / hexane / -78 °C

8.1: 90 percent / DMP / CH₂Cl₂ / 0 °C

With n-butyllithium; phthalic acid dimethyl ester; tetra-(n-butyl)ammonium iodide; sodium hydride; diisobutylaluminium hydride; ozone; In tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide; 6.1: Wittig reaction;
DOI:10.1016/S0040-4039(03)01173-0

Reference yield:

: 109121-41-7
(R)-4-((1S,2R)-1-benzyloxy-2-methylbut-3-enyl)-2,2-dimethyl-[1,3]dioxolane

: 596095-58-8
(2E,4E)-(6R,7S)-7-Benzyloxy-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,4,6-trimethyl-hepta-2,4-dienal

Guidance literature:: Multi-step reaction with 7 steps

1.1: O₃ / CH₂Cl₂ / -78 °C

1.2: 80 percent / PPh₃ / -25 °C

2.1: 70 percent / n-BuLi / tetrahydrofuran / -78 - 20 °C

3.1: 94 percent / DIBAL-H / hexane / -78 °C

4.1: 85 percent / DMP / CH₂Cl₂ / 0 °C

5.1: 65 percent / n-BuLi / tetrahydrofuran / -78 - 20 °C

6.1: 88 percent / DIBAL-H / hexane / -78 °C

7.1: 90 percent / DMP / CH₂Cl₂ / 0 °C

With n-butyllithium; phthalic acid dimethyl ester; diisobutylaluminium hydride; ozone; In tetrahydrofuran; hexane; dichloromethane; 5.1: Wittig reaction;
DOI:10.1016/S0040-4039(03)01173-0