4-Phosphonophenylglycine

Base Information

Chemical Name:4-Phosphonophenylglycine
CAS No.:120667-15-4
Molecular Formula:C₈H₁₀NO₅P
Molecular Weight:231.145
Hs Code.:
Mol file:120667-15-4.mol

Synonyms:Benzeneaceticacid, a-amino-4-phosphono-, (?à)-;(R,S)-4-Phosphonophenylglycine;(R,S)-PPG;4-Phosphonophenylglycine;

Suppliers and Price of 4-Phosphonophenylglycine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(RS)-PPG
5mg
$ 415.00

Tocris
(RS)-PPG
25
$ 292.00

Tocris
(RS)-PPG
5
$ 78.00

Sigma-Aldrich
(RS)-PPG ≥98% (HPLC)
25mg
$ 439.00

Sigma-Aldrich
(RS)-PPG ≥98% (HPLC)
5mg
$ 110.00

ApexBio Technology
(RS)-PPG
5mg
$ 150.00

ApexBio Technology
(RS)-PPG
25mg
$ 566.00

American Custom Chemicals Corporation
(R,S)-4-PHOSPHONOPHENYLGLYCINE 95.00%
50MG
$ 3775.00

American Custom Chemicals Corporation
(R,S)-4-PHOSPHONOPHENYLGLYCINE 95.00%
10MG
$ 1075.00

American Custom Chemicals Corporation
(R,S)-4-PHOSPHONOPHENYLGLYCINE 95.00%
5MG
$ 775.00

Total 13 raw suppliers

Chemical Property of 4-Phosphonophenylglycine

Chemical Property:

Vapor Pressure:1.85E-14mmHg at 25°C
Refractive Index:1.617
Boiling Point:583.5 °C at 760 mmHg
PKA:1.60±0.10(Predicted)
Flash Point:306.7 °C
PSA：130.66000
Density:1.58 g/cm³
LogP:0.27430
Storage Temp.:Store at RT
Solubility.:DMSO: soluble2mg/mL

Purity/Quality:

98%min ^*data from raw suppliers

(RS)-PPG ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (RS)-PPG is a potent and selective group III mGluR agonist.

Technology Process of 4-Phosphonophenylglycine

There total 4 articles about 4-Phosphonophenylglycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 289727-02-2
[4-(acetylamino-cyano-methyl)-phenyl]-phosphonic acid diethyl ester

: 289727-10-2,289727-11-3,120667-15-4
4-Phosphonophenylglycine

Guidance literature:: With hydrogenchloride; at 100 ℃; for 3h;
DOI:10.1016/S0960-894X(00)00197-9

Reference yield:

: [4-(amino-cyano-methyl)-phenyl]-phosphonic acid

: 289727-10-2,289727-11-3,120667-15-4
4-Phosphonophenylglycine

Guidance literature:: With hydrogenchloride;

Reference yield:

: 72436-45-4
(4-formylphenyl)phosphonic acid diethyl ester

: 289727-10-2,289727-11-3,120667-15-4
4-Phosphonophenylglycine

Guidance literature:: Multi-step reaction with 3 steps

1: NH₃; ZnI₂

2: pyridine

3: 85 percent / 20 percent aq. HCl / 3 h / 100 °C

With pyridine; hydrogenchloride; ammonia; zinc(II) iodide; 1: Condensation / 2: Acetylation / 3: Hydrolysis;
DOI:10.1016/S0960-894X(00)00197-9