289727-02-2Relevant academic research and scientific papers
(+)-4-Phosphonophenylglycine (PPG) a new group III selective metabotropic glutamate receptor agonist
Gasparini, Fabrizio,Inderbitzin, Werner,Francotte, Eric,Lecis, Gabrielle,Richert, Paul,Dragic, Zorica,Kuhn, Rainer,Flor, Peter J.
, p. 1241 - 1244 (2000)
A new synthesis of (R,S)-PPG (4-phosphonophenylglycine) and the separation of the protected enantiomers leading after deprotection to (+)- and (-)-PPG are described. Pharmacological characterization at the group III metabotropic glutamate receptors hmGluR4a and hmGluR7b revealed (+)-PPG as the active enantiomer. (C) 2000 Elsevier Science Ltd. All rights reserved.
