tert-butyl (1S,1'S)-1,1'-(5,5'-(4,4'-(ethyne-1,2-diyl)bis(4,1-phenylene))bis(1H-imidazole-5,2-diyl))bis(2,2-dimethylpropane-1,1-diyl)dicarbamate

Base Information

Chemical Name:tert-butyl (1S,1'S)-1,1'-(5,5'-(4,4'-(ethyne-1,2-diyl)bis(4,1-phenylene))bis(1H-imidazole-5,2-diyl))bis(2,2-dimethylpropane-1,1-diyl)dicarbamate
CAS No.:1447940-16-0
Molecular Formula:C₄₀H₅₂N₆O₄
Molecular Weight:680.891
Hs Code.:

Synonyms:tert-butyl (1S,1'S)-1,1'-(5,5'-(4,4'-(ethyne-1,2-diyl)bis(4,1-phenylene))bis(1H-imidazole-5,2-diyl))bis(2,2-dimethylpropane-1,1-diyl)dicarbamate

Suppliers and Price of tert-butyl (1S,1'S)-1,1'-(5,5'-(4,4'-(ethyne-1,2-diyl)bis(4,1-phenylene))bis(1H-imidazole-5,2-diyl))bis(2,2-dimethylpropane-1,1-diyl)dicarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl (1S,1'S)-1,1'-(5,5'-(4,4'-(ethyne-1,2-diyl)bis(4,1-phenylene))bis(1H-imidazole-5,2-diyl))bis(2,2-dimethylpropane-1,1-diyl)dicarbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl (1S,1'S)-1,1'-(5,5'-(4,4'-(ethyne-1,2-diyl)bis(4,1-phenylene))bis(1H-imidazole-5,2-diyl))bis(2,2-dimethylpropane-1,1-diyl)dicarbamate

There total 6 articles about tert-butyl (1S,1'S)-1,1'-(5,5'-(4,4'-(ethyne-1,2-diyl)bis(4,1-phenylene))bis(1H-imidazole-5,2-diyl))bis(2,2-dimethylpropane-1,1-diyl)dicarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: tert-butyl (2S,2'S)-1,1‘-(2,2'-(4,4'-(ethyne-1,2-diyl)bis(4,1-phenylene))bis(2-oxoethane-2,1-diyl))bis(azanediyl)bis(3,3-dimethyl-1-oxobutane-2,1-diyl)dicarbamate

: 1447940-16-0
tert-butyl (1S,1'S)-1,1'-(5,5'-(4,4'-(ethyne-1,2-diyl)bis(4,1-phenylene))bis(1H-imidazole-5,2-diyl))bis(2,2-dimethylpropane-1,1-diyl)dicarbamate

Guidance literature:: With ammonium acetate; In 5,5-dimethyl-1,3-cyclohexadiene; at 130 ℃; for 3h; Sealed tube;

Reference yield:

: 5467-72-1
α-amino-4-bromoacetophenone hydrochloride

: 1447940-16-0
tert-butyl (1S,1'S)-1,1'-(5,5'-(4,4'-(ethyne-1,2-diyl)bis(4,1-phenylene))bis(1H-imidazole-5,2-diyl))bis(2,2-dimethylpropane-1,1-diyl)dicarbamate

Guidance literature:: Multi-step reaction with 5 steps

1: N-ethyl-N,N-diisopropylamine; sodium hydrogencarbonate / dichloromethane / 2 h / 20 °C

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide / 4 h / 90 °C / Inert atmosphere

3: hydrogenchloride / 1,4-dioxane / 2 h / 20 °C

4: N-ethyl-N,N-diisopropylamine; HATU / dichloromethane / 3 h / 20 °C

5: ammonium acetate / 5,5-dimethyl-1,3-cyclohexadiene / 3 h / 130 °C / Sealed tube

With hydrogenchloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; ammonium acetate; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine; HATU; In 1,4-dioxane; 5,5-dimethyl-1,3-cyclohexadiene; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 62965-35-9
N-tert-butyloxycarbonyl-L-tert-leucine

: 1447940-16-0
tert-butyl (1S,1'S)-1,1'-(5,5'-(4,4'-(ethyne-1,2-diyl)bis(4,1-phenylene))bis(1H-imidazole-5,2-diyl))bis(2,2-dimethylpropane-1,1-diyl)dicarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine; HATU / dichloromethane / 3 h / 20 °C

2: ammonium acetate / 5,5-dimethyl-1,3-cyclohexadiene / 3 h / 130 °C / Sealed tube

With ammonium acetate; N-ethyl-N,N-diisopropylamine; HATU; In 5,5-dimethyl-1,3-cyclohexadiene; dichloromethane;