Technology Process of 4-cyano-3,5-dihexyloxybenzaldehyde
There total 6 articles about 4-cyano-3,5-dihexyloxybenzaldehyde which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 4h;
Inert atmosphere;
DOI:10.1039/c3ob40452h
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: tetrabutylammomium bromide; potassium carbonate / acetone / 18 h / Reflux
2.1: N,N-dimethyl-formamide / 48 h / 150 - 160 °C
3.1: tetrabutylammomium bromide; lithium hydroxide monohydrate / tetrahydrofuran; methanol / 18 h
4.1: 4-methyl-morpholine / dichloromethane / 0.33 h / 0 °C
4.2: 1 h / 0 °C
5.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere
With
4-methyl-morpholine; lithium aluminium tetrahydride; lithium hydroxide monohydrate; tetrabutylammomium bromide; potassium carbonate;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; acetone;
1.1: |Williamson Ether Synthesis;
DOI:10.1039/c3ob40452h
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: N,N-dimethyl-formamide / 48 h / 150 - 160 °C
2.1: tetrabutylammomium bromide; lithium hydroxide monohydrate / tetrahydrofuran; methanol / 18 h
3.1: 4-methyl-morpholine / dichloromethane / 0.33 h / 0 °C
3.2: 1 h / 0 °C
4.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere
With
4-methyl-morpholine; lithium aluminium tetrahydride; lithium hydroxide monohydrate; tetrabutylammomium bromide;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/c3ob40452h
