34126-16-4

Basic information

• Product Name: methyl 4-bromo-3,5-dihydroxy-benzoate
• Synonyms: 3,5-Dihydroxy-4-bromobenzoic acid methyl ester
• CAS NO: 34126-16-4
• Molecular Formula: C₈H₇BrO₄
• Molecular Weight: 247.04
• Mol File: 34126-16-4.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 384.4 °C at 760 mmHg
• Flash Point: 186.3 °C
• Appearance: /
• Density: 1.759 g/cm³
• Vapor Pressure: 1.85E-06mmHg at 25°C
• Refractive Index: 1.622
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: methyl 4-bromo-3,5-dihydroxy-benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-bromo-3,5-dihydroxy-benzoate(34126-16-4)
• EPA Substance Registry System: methyl 4-bromo-3,5-dihydroxy-benzoate(34126-16-4)

Safety Data

• Hazardous Substances Data: 34126-16-4(Hazardous Substances Data)

Usage

General Description

Methyl 4-bromo-3,5-dihydroxy-benzoate, also known as bromohydroxybenzoic acid methyl ester, is a chemical compound with the molecular formula C8H7BrO4. It is a derivative of benzoic acid that contains a bromine atom and two hydroxyl groups. methyl 4-bromo-3,5-dihydroxy-benzoate is commonly used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It has been studied for its potential biological activities, including anti-inflammatory and antioxidant properties. Methyl 4-bromo-3,5-dihydroxy-benzoate is also used as a reagent in organic chemistry and is commercially available for research and industrial applications.

InChI:InChI=1/C8H7BrO4/c1-13-8(12)4-2-5(10)7(9)6(11)3-4/h2-3,10-11H,1H3

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 16534-12-6 3,5-dihydroxy-4-bromobenzoic acid 
• 99-10-5 3,5-Dihydroxybenzoic acid 
• 67-56-1 methanol 

Downstream Products

• 331943-76-1 [4-bromo-3,5-bis-(2-trimethylsilanyl-ethoxymethoxy)-phenyl]-methanol 
• 331943-78-3 2-bromo-5-methoxymethyl-1,3-bis[(2-trimethylsilylethoxy)methoxy]-benzene 
• 934990-97-3 2,6-bis(hex-5-enyloxy)-4-(2-tetrahydropyranyloxymethyl)phenylboronic acid 
• 934990-28-0 4-(tert-butyldimethylsilyloxymethyl)-2,6-bis(pent-4-enyloxy)phenylboronic acid 
• 934990-92-8 2-bromo-1,3-bis(hex-5-enyloxy)-5-(2-tetrahydropyranyloxymethyl)benzene 
• 934990-24-6 2-bromo-5-(tert-butyldimethylsilyloxymethyl)-1,3-bis(pent-4-enyloxy)benzene 
• 934990-86-0 4-bromo-3,5-bis(hex-5-enyloxy)phenylmethanol 
• 934990-20-2 4-bromo-3,5-bis(pent-4-enyloxy)phenylmethanol 
• 934990-73-5 methyl 3-({2,13,15,26-tetraoxa-1,14(1,3,2)-dibenzena-27(2,6)-pyridinabicyclo[12.12.1]heptacosaphan-1⁵-yl}methyloxy)benzoate 
• 1027076-29-4 2-[2,6-bis(hex-5-enyloxy)phenyl]-6-[2,6-bis(hex-5-enyloxy)-4-(hydroxymethyl)phenyl]pyridine 
• 934990-51-9 methyl 3-({2,11,13,22-tetraoxa-1,12(1,3,2)-dibenzena-23(2,6)-pyridinabicyclo[10.10.1]tricosaphan-6,17-dien-1⁵-yl}methyloxy)benzoate 
• 934991-07-8 2-[2,6-bis(hex-5-enyloxy)phenyl]-6-[2,6-bis(hex-5-enyloxy)-4-(2-tetrahydropyranyloxymethyl)phenyl]pyridine 
• 934990-38-2 2-[2,6-bis(pent-4-enyloxy)phenyl]-6-[2,6-bis(pent-4-enyloxy)-4-(tert-butyldimethylsilyloxymethyl)phenyl]pyridine 
• 934990-79-1 methyl 4-bromo-3,5-bis(hex-5-enyloxy)benzoate 

Relevant articles and documents

Impact of substitution pattern and chain length on the thermotropic properties of alkoxy-substituted triphenyl-tristriazolotriazines

Tristriazolotriazines (TTTs) with a threefold alkoxyphenyl substitution were prepared and studied by DSC, polarized optical microscopy (POM) and X-ray scattering. Six pentyloxy chains are sufficient to induce liquid-crystalline behavior in these star-shap

Total Synthesis of Gramistilbenoids A, B, and C

Stilbenes are biologically active metabolites of plants that have the potential to attenuate a broad range of human diseases. Gramistilbenoids are a class of natural products with a stilbene skeleton, isolated from the bamboo orchid (Arundina graminifolia), and with significant cytotoxicity against cancer cell lines (NB4, A549, SHSY5Y, PC3, and MCF7). These are the first identified naturally occurring diphenylethylenes to possess a hydroxyethyl unit. However, some of these compounds are not abundant in nature, and thus, their synthesis is advantageous. This paper reports the first synthesis of gramistilbenoids A (1), B (2), and C (3), with overall yields of 10, 2, and 8% respectively. These natural products were synthesized using key reactions, such as Horner-Wadsworth-Emmons olefination, Stille coupling, and hydroboration-oxidation.

Heterocyclic compound and application thereof

The invention belongs to the field of medical chemistry, and relates to a heterocyclic compound and application thereof. Concretely, the invention provides a compound as shown in a formula I, or an isomer, pharmaceutically acceptable salts, and a solvate