4-Chloro-N-(1-(3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazol-4-yl)ethyl)benzenesulfonamide

Base Information

Chemical Name:4-Chloro-N-(1-(3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazol-4-yl)ethyl)benzenesulfonamide
CAS No.:959996-63-5
Molecular Formula:C₁₇H₂₅ClIN₃O₃SSi
Molecular Weight:541.913
Hs Code.:

Synonyms:4-Chloro-N-(1-(3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazol-4-yl)ethyl)benzenesulfonamide

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Chemical Property of 4-Chloro-N-(1-(3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazol-4-yl)ethyl)benzenesulfonamide

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Technology Process of 4-Chloro-N-(1-(3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazol-4-yl)ethyl)benzenesulfonamide

There total 1 articles about 4-Chloro-N-(1-(3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazol-4-yl)ethyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 959996-62-4
1-(3-Iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazol-4-yl)ethanamine

: 98-60-2
4-chlorobenzenesulfonyl chloride

: 959996-63-5
4-Chloro-N-(1-(3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazol-4-yl)ethyl)benzenesulfonamide

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 20 ℃; for 4h;

Reference yield: 80.0%

: 16681-56-4,151223-74-4
2-bromo-1H-imidazole

: 959996-63-5
4-Chloro-N-(1-(3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazol-4-yl)ethyl)benzenesulfonamide

: 959996-64-6
(5-(4-chlorophenylsulfonyl)-4-methyl-1-((2-trimethylsilyl)ethoxy)methyl)-4,5-dihydro-1H-imidazo[1,2-a]pyrazolo[4,3-e]pyrimidine

Guidance literature:: With trans-N,N'-dimethyl-1,2-cyclohexyldiamine; copper(l) iodide; caesium carbonate; In 1,4-dioxane; at 110 ℃; for 1h;

Reference yield: 70.0%

: 16681-56-4,151223-74-4
2-bromo-1H-imidazole

: 959996-63-5
4-Chloro-N-(1-(3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazol-4-yl)ethyl)benzenesulfonamide

: 1190854-01-3
C₂₀H₂₆ClN₅O₃SSi

Guidance literature:: With copper(l) iodide; caesium carbonate; trans-N,N'-dimethylcyclohexane-1,2-diamine; In 1,4-dioxane; Reflux;
DOI:10.1016/j.bmcl.2009.07.092