8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine

Base Information

Chemical Name:8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
CAS No.:616201-80-0
Molecular Formula:C11H14Cl N
Molecular Weight:195.692
Hs Code.:
DSSTox Substance ID:DTXSID90440335,DTXSID30861560
Pharos Ligand ID:C2RBV4M8FKPA
Metabolomics Workbench ID:143813
ChEMBL ID:CHEMBL181172
Mol file:616201-80-0.mol

Synonyms:616201-80-0;Lorcaserin A;8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine;LorcaserinA;1H-3-Benzazepine, 8-chloro-2,3,4,5-tetrahydro-1-methyl-;7-chloro-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine;CHEMBL181172;8-CHLORO-1-METHYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE;1H-3-Benzazepine, 8-chloro-2,3,4,5-tetrahydro-1-methyl-, (1S)-;SCHEMBL170848;1H-3-Benzazepine,8-chloro-2,3,4,5-tetrahydro-1-methyl-;DTXSID30861560;DTXSID90440335;XTTZERNUQAFMOF-UHFFFAOYSA-N;HMS3750C11;AMY42081;BCP04102;BCP12980;CS-M1985;BDBM50161628;MFCD09833669;AKOS006326203;AB52743;AB52744;SB16626;AS-41614;FT-0696347;A12378;A868668;L023561;ETHYL3-[(HYDRAZINOTHIOXOMETHYL)AMINO]BENZOATE;(1R,S)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine

Suppliers and Price of 8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[D]azepine
50mg
$ 130.00

Crysdot
8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine 95+%
250mg
$ 338.00

Crysdot
8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine 95+%
1g
$ 845.00

Chemenu
8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine 95%
1g
$ 791.00

Biosynth Carbosynth
8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
500 mg
$ 365.00

Biosynth Carbosynth
8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
250 mg
$ 210.00

Biosynth Carbosynth
8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
100 mg
$ 106.00

Biosynth Carbosynth
8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
50 mg
$ 61.00

Biosynth Carbosynth
8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
1 g
$ 637.50

American Custom Chemicals Corporation
8-CHLORO-1-METHYL-2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE 95.00%
5MG
$ 495.56

Total 67 raw suppliers

Chemical Property of 8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine

Chemical Property:

Boiling Point:288ºC
PKA:9.99±0.40(Predicted)
Flash Point:128 ºC
PSA：12.03000
Density:1.075g/cm³
LogP:2.91800
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:195.0814771
Heavy Atom Count:13
Complexity:172

Purity/Quality:

99%+ ^*data from raw suppliers

8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[D]azepine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CNCCC2=C1C=C(C=C2)Cl

Technology Process of 8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine

There total 33 articles about 8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 953789-37-2
1-[[2-(4-chlorophenyl)ethyl]amino]-2-chloropropane hydrochloride

: 616201-80-0,616202-92-7
(+/-)-Lorcaserin

Guidance literature:: With aluminum (III) chloride; In 1,2-dichloro-benzene; at 120 - 125 ℃; Inert atmosphere;

Reference yield: 92.3%

: N-(4-chlorophenylethyl)propyl-2-ene-1-amine hydrochloride

: 616201-80-0,616202-92-7
(+/-)-Lorcaserin

Guidance literature:: With aluminum (III) chloride; In 1,2-dichloro-benzene; at 110 ℃; for 4h; Solvent; Temperature; Reagent/catalyst; Inert atmosphere; Large scale;
DOI:10.1021/acs.oprd.5b00144