Technology Process of (E)-2-ethyl-2-hydroxy-N,N-diethyl-4-(phenylsulfonyl)but-3-enamide
There total 3 articles about (E)-2-ethyl-2-hydroxy-N,N-diethyl-4-(phenylsulfonyl)but-3-enamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
at 0 ℃;
for 2h;
Inert atmosphere;
DOI:10.1016/j.tet.2011.02.017
- Guidance literature:
-
Multi-step reaction with 2 steps
1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1.5 h / Inert atmosphere
2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 0 °C / Inert atmosphere
With
tetrabutyl ammonium fluoride; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; dichloromethane;
DOI:10.1016/j.tet.2011.02.017
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: tetrahydrofuran / 2.5 h / -65 - -30 °C / Inert atmosphere
1.2: Inert atmosphere
2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1.5 h / Inert atmosphere
3.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 0 °C / Inert atmosphere
With
tetrabutyl ammonium fluoride; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; dichloromethane;
DOI:10.1016/j.tet.2011.02.017
