1-[4-BROMO-2-(HYDROXYMETHYL)PHENYL]-4-(DIMETHYLAMINO)-1-(4-FLUOROPHENYL) BUTAN-1-OL HYDROCHLORIDE

Base Information

Chemical Name:1-[4-BROMO-2-(HYDROXYMETHYL)PHENYL]-4-(DIMETHYLAMINO)-1-(4-FLUOROPHENYL) BUTAN-1-OL HYDROCHLORIDE
CAS No.:508169-73-1
Molecular Formula:C19H23 Br F N O2 . Cl H
Molecular Weight:432.75
Hs Code.:
Mol file:508169-73-1.mol

Synonyms:1,2-Benzenedimethanol,4-bromo-a1-[3-(dimethylamino)propyl]-a1-(4-fluorophenyl)-,hydrochloride (9CI)

Suppliers and Price of 1-[4-BROMO-2-(HYDROXYMETHYL)PHENYL]-4-(DIMETHYLAMINO)-1-(4-FLUOROPHENYL) BUTAN-1-OL HYDROCHLORIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-[4-BROMO-2-(HYDROXYMETHYL)PHENYL]-4-(DIMETHYLAMINO)-1-(4-FLUOROPHENYL)BUTAN-1-OL HYDROCHLORIDE 95.00%
5MG
$ 499.77

Total 9 raw suppliers

Chemical Property of 1-[4-BROMO-2-(HYDROXYMETHYL)PHENYL]-4-(DIMETHYLAMINO)-1-(4-FLUOROPHENYL) BUTAN-1-OL HYDROCHLORIDE

Chemical Property:

PSA：43.70000
LogP:4.46020

Purity/Quality:

99% ^*data from raw suppliers

1-[4-BROMO-2-(HYDROXYMETHYL)PHENYL]-4-(DIMETHYLAMINO)-1-(4-FLUOROPHENYL)BUTAN-1-OL HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-[4-BROMO-2-(HYDROXYMETHYL)PHENYL]-4-(DIMETHYLAMINO)-1-(4-FLUOROPHENYL) BUTAN-1-OL HYDROCHLORIDE

There total 1 articles about 1-[4-BROMO-2-(HYDROXYMETHYL)PHENYL]-4-(DIMETHYLAMINO)-1-(4-FLUOROPHENYL) BUTAN-1-OL HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.4%

: 19070-16-7
3-(N,N-dimethylamino)propylmagnesium chloride

: 64169-34-2
5-bromophthalide

: 352-13-6
4-flourophenylmagnesium bromide

: 508169-73-1
(4-bromo-2-hydroxyethyl) phenyl-(4-fluorophenyl)-(3-dimethylaminopropyl) methanol hydrochloride

Guidance literature:: 5-bromophthalide; 4-flourophenylmagnesium bromide; In tetrahydrofuran; toluene; at 20 ℃; for 1.5h; Heating / reflux;

3-(N,N-dimethylamino)propylmagnesium chloride; In tetrahydrofuran; toluene; at 20 - 30 ℃; for 18h;

With hydrogenchloride; In tetrahydrofuran; water; toluene; at 20 ℃; for 1h;

Reference yield: 99.2%

: 508169-73-1
(4-bromo-2-hydroxyethyl) phenyl-(4-fluorophenyl)-(3-dimethylaminopropyl) methanol hydrochloride

: 64169-39-7
3-(5-bromo-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-1-yl)-N,N-dimethylpropan-1-amine

Guidance literature:: (4-bromo-2-hydroxyethyl) phenyl-(4-fluorophenyl)-(3-dimethylaminopropyl) methanol hydrochloride; With phosphoric acid; In water; at 90 ℃; for 1h; Heating / reflux;

With ammonia; In water; toluene; at 10 - 25 ℃;