7-O-(tert-butyldiphenylsilyl)morpholinocytidine

Base Information

Chemical Name:7-O-(tert-butyldiphenylsilyl)morpholinocytidine
CAS No.:1415645-50-9
Molecular Formula:C₂₅H₃₂N₄O₃Si
Molecular Weight:464.64
Hs Code.:

Synonyms:7-O-(tert-butyldiphenylsilyl)morpholinocytidine

Suppliers and Price of 7-O-(tert-butyldiphenylsilyl)morpholinocytidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 7-O-(tert-butyldiphenylsilyl)morpholinocytidine

Chemical Property:

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 7-O-(tert-butyldiphenylsilyl)morpholinocytidine

There total 8 articles about 7-O-(tert-butyldiphenylsilyl)morpholinocytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 58479-65-5
5'-O-(tert-butyldiphenylsilyl)cytidine

: 1415645-50-9
7-O-(tert-butyldiphenylsilyl)morpholinocytidine

Guidance literature:: 5'-O-(tert-butyldiphenylsilyl)cytidine; With sodium periodate; ammonium biborate tetrahydrate; In methanol; at 20 ℃; for 1.5h; Molecular sieve; Inert atmosphere;

With sodium cyanoborohydride; acetic acid; In methanol; for 2h; Molecular sieve; Inert atmosphere;
DOI:10.1080/15257770.2012.724491

Reference yield: 20.0%

: 1415645-56-5
7-O-(tert-butyldiphenylsilyl)-N-trityl morpholinocytidine

: 1415645-50-9
7-O-(tert-butyldiphenylsilyl)morpholinocytidine

: 1429479-79-7
C₄₄H₄₅IN₄O₃Si

Guidance literature:: With N-iodo-succinimide; In methanol; at 65 ℃; for 6h; Reagent/catalyst; Solvent; Time; Temperature;
DOI:10.1002/ejoc.201201384

Reference yield:

: 1429479-77-5
C₂₇H₃₁F₃N₄O₄Si

: 1415645-50-9
7-O-(tert-butyldiphenylsilyl)morpholinocytidine

Guidance literature:: Multi-step reaction with 5 steps

1: acetic acid; iodine; iodic acid / tetrachloromethane / 55 h / 40 °C

2: potassium carbonate; methanol / 3 h / 20 °C

3: triethylamine / dichloromethane / 5 - 20 °C / Inert atmosphere

4: potassium carbonate; bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide / 16 h / 90 °C

5: N-iodo-succinimide / methanol / 6 h / 65 °C

With methanol; bis-triphenylphosphine-palladium(II) chloride; N-iodo-succinimide; iodine; iodic acid; potassium carbonate; acetic acid; triethylamine; In methanol; tetrachloromethane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/ejoc.201201384