(4-Nitrophenyl)(oxo)acetyl chloride

Base Information

Chemical Name:(4-Nitrophenyl)(oxo)acetyl chloride
CAS No.:105248-77-9
Molecular Formula:C₈H₄ClNO₄
Molecular Weight:213.577
Hs Code.:
DSSTox Substance ID:DTXSID80569100
Wikidata:Q82455816
Mol file:105248-77-9.mol

Synonyms:105248-77-9;2-(4-nitrophenyl)-2-oxoacetyl chloride;Benzeneacetyl chloride, 4-nitro-alpha-oxo- (9CI);(4-Nitrophenyl)(oxo)acetyl chloride;SCHEMBL9486193;DTXSID80569100

Suppliers and Price of (4-Nitrophenyl)(oxo)acetyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Atlantic Research Chemicals
2-(4-Nitrophenyl)-2-oxoacetylchloride 95%
1gm:
$ 378.20

Total 1 raw suppliers

Chemical Property of (4-Nitrophenyl)(oxo)acetyl chloride

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:212.9828853
Heavy Atom Count:14
Complexity:265

Purity/Quality:: 2-(4-Nitrophenyl)-2-oxoacetylchloride 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)C(=O)Cl)[N+](=O)[O-]

Technology Process of (4-Nitrophenyl)(oxo)acetyl chloride

There total 3 articles about (4-Nitrophenyl)(oxo)acetyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 14922-36-2
4-nitrophenylglyoxylic acid

: 105248-77-9
4-nitro-α-oxophenylacetyl chloride

Guidance literature:: With oxalyl dichloride; In dichloromethane; N,N-dimethyl-formamide; at 45 ℃; for 1.03333h; Inert atmosphere;
DOI:10.1016/j.dyepig.2019.02.042

Reference yield:

: 57699-27-1
methyl p-nitrophenylglyoxylate

: 105248-77-9
4-nitro-α-oxophenylacetyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: KOH / H₂O; ethanol

2: oxalyl chloride / CH₂Cl₂ / 0.5 h / cooling

With potassium hydroxide; oxalyl dichloride; In ethanol; dichloromethane; water;
DOI:10.1021/jo070575f

Reference yield:

: 100-19-6
(4-nitrophenyl)ethanone

: 105248-77-9
4-nitro-α-oxophenylacetyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: selenium(IV) oxide; pyridine / 1 h / 110 °C / Inert atmosphere

2: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 45 °C / Inert atmosphere

With pyridine; selenium(IV) oxide; oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane;