N-(4-bromo-2,6-dimethylphenyl)-N'-(2,4,6-trimethylphenyl)ethane-1,2-diamineoxamide

Base Information

• Chemical Name: N-(4-bromo-2,6-dimethylphenyl)-N'-(2,4,6-trimethylphenyl)ethane-1,2-diamineoxamide
• CAS No.: 868961-60-8
• Molecular Formula: C₁₉H₂₅BrN₂
• Molecular Weight: 361.325

Synonyms:N-(4-bromo-2,6-dimethylphenyl)-N'-(2,4,6-trimethylphenyl)ethane-1,2-diamineoxamide

Chemical Property of N-(4-bromo-2,6-dimethylphenyl)-N'-(2,4,6-trimethylphenyl)ethane-1,2-diamineoxamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-bromo-2,6-dimethylphenyl)-N'-(2,4,6-trimethylphenyl)ethane-1,2-diamineoxamide

There total 5 articles about N-(4-bromo-2,6-dimethylphenyl)-N'-(2,4,6-trimethylphenyl)ethane-1,2-diamineoxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

N-(4-bromo-2,6-dimethylphenyl)-N'-(2,4,6-trimethylphenyl)oxamide (868961-35-7) → N-(4-bromo-2,6-dimethylphenyl)-N'-(2,4,6-trimethylphenyl)ethane-1,2-diamineoxamide (868961-60-8)

Guidance literature:

N-(4-bromo-2,6-dimethylphenyl)-N'-(2,4,6-trimethylphenyl)oxamide; With dimethylsulfide borane complex; In toluene; at 95 ℃; for 18h;

With hydrogenchloride; In toluene; pH=3;

With triethylamine; In dichloromethane; at 20 ℃; for 7h;

DOI:10.1021/ol0516521

Reference yield:

oxo-(2,4,6-trimethylphenylamino)acetyl chloride (868961-34-6) → N-(4-bromo-2,6-dimethylphenyl)-N'-(2,4,6-trimethylphenyl)ethane-1,2-diamineoxamide (868961-60-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 73 percent / Et₃N / CH₂Cl₂ / 15 h / 20 °C

2.1: BH₃*Me₂S / toluene / 18 h / 95 °C

2.2: aq. HCl / toluene / pH 3

2.3: 58 percent / Et₃N / CH₂Cl₂ / 7 h / 20 °C

With dimethylsulfide borane complex; triethylamine; In dichloromethane; toluene;

DOI:10.1021/ol0516521

Reference yield:

4-bromo-2,6-dimethylphenylamine (24596-19-8) → N-(4-bromo-2,6-dimethylphenyl)-N'-(2,4,6-trimethylphenyl)ethane-1,2-diamineoxamide (868961-60-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 73 percent / Et₃N / CH₂Cl₂ / 15 h / 20 °C

2.1: BH₃*Me₂S / toluene / 18 h / 95 °C

2.2: aq. HCl / toluene / pH 3

2.3: 58 percent / Et₃N / CH₂Cl₂ / 7 h / 20 °C

With dimethylsulfide borane complex; triethylamine; In dichloromethane; toluene;

DOI:10.1021/ol0516521

upstream raw materials:

N-(4-bromo-2,6-dimethylphenyl)-N'-(2,4,6-trimethylphenyl)oxamide

oxo-(2,4,6-trimethylphenylamino)acetyl chloride

4-bromo-2,6-dimethylphenylamine

2,4,6-trimethylaniline

Downstream raw materials:

C₂₇H₃₆Cl₃N₃O₂

C₂₀H₂₅N₃

C₂₆H₃₆N₃O₂⁽¹⁺⁾*Cl^(1-)

C₂₅H₃₇N₃O₂

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 868961-60-8 N-(4-bromo-2,6-dimethylphenyl)-N'-(2,4,6-trimethylphenyl)ethane-1,2-diamineoxamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send