N2,N2-Dimethyl-2,3-pyridinediamine

Base Information

• Chemical Name: N2,N2-Dimethyl-2,3-pyridinediamine
• CAS No.: 5028-25-1
• Molecular Formula: C₇H₁₁N₃
• Molecular Weight: 137.184
• Mol file: 5028-25-1.mol

Synonyms:3-Amino-2-dimethylaminopyridine

Chemical Property of N2,N2-Dimethyl-2,3-pyridinediamine

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

N2,N2-dimethyl-2,3-pyridinediamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N2,N2-Dimethyl-2,3-pyridinediamine

There total 6 articles about N2,N2-Dimethyl-2,3-pyridinediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N,N-dimethyl-3-nitropyridin-2-amine (5028-23-9) → 3-Amino-2-dimethylaminopyridine (5028-25-1)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In methanol; ethyl acetate; under 2585.81 Torr;

Reference yield:

tin(II)chloride dihydrate + N,N-dimethyl-3-nitropyridin-2-amine (5028-23-9) → 3-Amino-2-dimethylaminopyridine (5028-25-1)

Guidance literature:

With sodium hydrogencarbonate; In ethanol;

Reference yield:

n-Pent-4-enyl alcohol (821-09-0) → 3-Amino-2-dimethylaminopyridine (5028-25-1)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydride / N,N-dimethyl-formamide / 100 °C

2: hydrogen / palladium 10% on activated carbon / methanol; ethyl acetate / 2585.81 Torr

With hydrogen; sodium hydride; palladium 10% on activated carbon; In methanol; ethyl acetate; N,N-dimethyl-formamide;

upstream raw materials:

2-chloro-3-aminopyridine

dimethyl amine

N,N-dimethyl-3-nitropyridin-2-amine

n-Pent-4-enyl alcohol

Refernces

• 1、 -. "ANTI-CANCER AGENTS ANS USES THEREOF". Page/Page column 156. . Retrieved 2010/11/29.
• 2、 -. "Anti-cancer agents and uses thereof". Page/Page column 53. . Retrieved 2008/06/13.