3-(3-(6-bromohexyloxy)phenyl)-3-(trifluoromethyl)-3H-diazirine

Base Information

• Chemical Name: 3-(3-(6-bromohexyloxy)phenyl)-3-(trifluoromethyl)-3H-diazirine
• CAS No.: 1393743-77-5
• Molecular Formula: C₁₄H₁₆BrF₃N₂O
• Molecular Weight: 365.193
• Mol file: 1393743-77-5.mol

Synonyms:3-(3-(6-bromohexyloxy)phenyl)-3-(trifluoromethyl)-3H-diazirine

Chemical Property of 3-(3-(6-bromohexyloxy)phenyl)-3-(trifluoromethyl)-3H-diazirine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(3-(6-bromohexyloxy)phenyl)-3-(trifluoromethyl)-3H-diazirine

There total 7 articles about 3-(3-(6-bromohexyloxy)phenyl)-3-(trifluoromethyl)-3H-diazirine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1 ,6-dibromohexane (629-03-8) + 3-(3-hydroxyhenyl)-3-(trifluoromethyl)-3H-diazirine (113787-85-2) → 3-(3-(6-bromohexyloxy)phenyl)-3-(trifluoromethyl)-3H-diazirine (1393743-77-5)

Guidance literature:

With potassium carbonate; In acetone; at 55 ℃; Reflux;

Reference yield:

2,2,2-trifluoro-1-(3-methoxyphenyl)-N-{[(4-methylphenyl)sulfonyl]oxy}ethanimine (877667-30-6) → 3-(3-(6-bromohexyloxy)phenyl)-3-(trifluoromethyl)-3H-diazirine (1393743-77-5)

Guidance literature:

Multi-step reaction with 4 steps

1: ammonia / dichloromethane / 12 h / -34 °C

2: silver(l) oxide / diethyl ether / 12 h / 23 °C

3: boron tribromide / dichloromethane / 7 h / 0 °C

4: potassium carbonate / acetone / 55 °C / Reflux

With ammonia; boron tribromide; potassium carbonate; silver(l) oxide; In diethyl ether; dichloromethane; acetone;

Reference yield:

2,2,2-trifluoro-1-(3-methoxyphenyl)ethanone (30724-22-2) → 3-(3-(6-bromohexyloxy)phenyl)-3-(trifluoromethyl)-3H-diazirine (1393743-77-5)

Guidance literature:

Multi-step reaction with 6 steps

1: pyridine; hydroxylamine hydrochloride / ethanol / 14 h / 60 °C

2: dmap; triethylamine / dichloromethane / 1 h / 0 °C

3: ammonia / dichloromethane / 12 h / -34 °C

4: silver(l) oxide / diethyl ether / 12 h / 23 °C

5: boron tribromide / dichloromethane / 7 h / 0 °C

6: potassium carbonate / acetone / 55 °C / Reflux

With pyridine; dmap; hydroxylamine hydrochloride; ammonia; boron tribromide; potassium carbonate; triethylamine; silver(l) oxide; In diethyl ether; ethanol; dichloromethane; acetone;

upstream raw materials:

2,2,2-trifluoro-1-(3-methoxyphenyl)-N-{[(4-methylphenyl)sulfonyl]oxy}ethanimine

3-(3-Methoxyphenyl)-3-(trifluoromethyl)diaziridine

3-(3-methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine

1 ,6-dibromohexane

Downstream raw materials:

3-(3-(6-iodohexyloxy)phenyl)-3-(trifluoromethyl)-3H-diazirine

C₃₄H₄₁F₂₁N₂OP⁽¹⁺⁾*Br^(1-)

3-(3-(6-bromohexyloxy)phenyl)-3-(trifluoromethyl)-3H-diazirine

Refernces