tert-butyl 3-{[(3-amino-2-chloroquinolin-4-yl)amino]methyl}benzylcarbamate

Base Information

Chemical Name:tert-butyl 3-{[(3-amino-2-chloroquinolin-4-yl)amino]methyl}benzylcarbamate
CAS No.:936544-93-3
Molecular Formula:C₂₂H₂₅ClN₄O₂
Molecular Weight:412.919
Hs Code.:

Synonyms:tert-butyl 3-{[(3-amino-2-chloroquinolin-4-yl)amino]methyl}benzylcarbamate

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Chemical Property of tert-butyl 3-{[(3-amino-2-chloroquinolin-4-yl)amino]methyl}benzylcarbamate

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Technology Process of tert-butyl 3-{[(3-amino-2-chloroquinolin-4-yl)amino]methyl}benzylcarbamate

There total 3 articles about tert-butyl 3-{[(3-amino-2-chloroquinolin-4-yl)amino]methyl}benzylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 936544-92-2
tert-butyl 3-{[(2-chloro-3-nitroquinolin-4-yl)amino]methyl}benzylcarbamate

: 936544-93-3
tert-butyl 3-{[(3-amino-2-chloroquinolin-4-yl)amino]methyl}benzylcarbamate

Guidance literature:: With hydrogen; platinum on carbon; In acetonitrile; under 1551.49 Torr;

Reference yield:

: 108467-99-8
1-(N-Boc-aminomethyl)-3-(aminomethyl)benzene

: 936544-93-3
tert-butyl 3-{[(3-amino-2-chloroquinolin-4-yl)amino]methyl}benzylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane; methanol / 0.5 h / 45 °C

2: hydrogen; sodium sulfate / platinum on activated charcoal / ethyl acetate / 4 h / 2844.39 Torr

With hydrogen; sodium sulfate; triethylamine; platinum on activated charcoal; In methanol; dichloromethane; ethyl acetate;

Reference yield:

: 132521-66-5
2,4-dichloro-3-nitroquinoline

: 936544-93-3
tert-butyl 3-{[(3-amino-2-chloroquinolin-4-yl)amino]methyl}benzylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane; methanol / 0.5 h / 45 °C

2: hydrogen; sodium sulfate / platinum on activated charcoal / ethyl acetate / 4 h / 2844.39 Torr

With hydrogen; sodium sulfate; triethylamine; platinum on activated charcoal; In methanol; dichloromethane; ethyl acetate;