2,4-Dichloro-3-nitroquinoline

Base Information

Chemical Name:2,4-Dichloro-3-nitroquinoline
CAS No.:132521-66-5
Molecular Formula:C9H4Cl2N2O2
Molecular Weight:243.049
Hs Code.:2933499090
European Community (EC) Number:819-859-5
DSSTox Substance ID:DTXSID90382862
Wikidata:Q82174329
Mol file:132521-66-5.mol

Synonyms:2,4-dichloro-3-nitroquinoline;132521-66-5;2,4-dichloro-3-nitro-quinoline;Quinoline, 2,4-dichloro-3-nitro-;2,4-dichloro-3-nitro quinoline;MFCD05666285;SCHEMBL159319;DTXSID90382862;RSFJVCHKGRUCIC-UHFFFAOYSA-N;AKOS000320153;AB22422;AC-18616;AS-43339;SY248818;CS-0060571;FT-0759082;EN300-177344;A901561;A1-39922

Suppliers and Price of 2,4-Dichloro-3-nitroquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,4-Dichloro-3-nitroquinoline
50mg
$ 125.00

SynQuest Laboratories
2,4-Dichloro-3-nitroquinoline
250 mg
$ 376.00

SynQuest Laboratories
2,4-Dichloro-3-nitroquinoline
1 g
$ 824.00

Matrix Scientific
2,4-Dichloro-3-nitroquinoline 97%
1g
$ 495.00

Crysdot
2,4-Dichloro-3-nitroquinoline 95+%
1g
$ 470.00

Chemenu
2,4-Dichloro-3-nitroquinoline 95+%
25g
$ 1150.00

American Custom Chemicals Corporation
2,4-DICHLORO-3-NITRO-QUINOLINE 97.00%
1G
$ 1022.18

Ambeed
2,4-Dichloro-3-nitroquinoline 95%
5g
$ 546.00

Ambeed
2,4-Dichloro-3-nitroquinoline 95%
1g
$ 160.00

Ambeed
2,4-Dichloro-3-nitroquinoline 95%
100mg
$ 41.00

Total 22 raw suppliers

Chemical Property of 2,4-Dichloro-3-nitroquinoline

Chemical Property:

Vapor Pressure:4.84E-05mmHg at 25°C
Melting Point:102 °C(Solv: methanol (67-56-1); ethyl acetate (141-78-6))
Refractive Index:1.693
Boiling Point:359.7°C at 760 mmHg
PKA:-4.98±0.50(Predicted)
Flash Point:171.3°C
PSA：58.71000
Density:1.593g/cm³
LogP:3.97300
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:241.9649828
Heavy Atom Count:15
Complexity:259

Purity/Quality:

99%, ^*data from raw suppliers

2,4-Dichloro-3-nitroquinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=C(C(=N2)Cl)[N+](=O)[O-])Cl
Uses 2,4-Dichloro-3-nitroquinoline has antitumor activity.

Technology Process of 2,4-Dichloro-3-nitroquinoline

There total 7 articles about 2,4-Dichloro-3-nitroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 15151-57-2
2,4-dihydroxy-3-nitroquinoline

: 132521-66-5
2,4-dichloro-3-nitroquinoline

Guidance literature:: With trichlorophosphate; at 100 ℃; Inert atmosphere;

Reference yield:

: 15151-57-2
4-hydroxy-3-nitro-1,2-dihydroquinolin-2-one

: 132521-66-5
2,4-dichloro-3-nitroquinoline

Guidance literature:: With triethylamine; trichlorophosphate; for 0.5h; Heating;
DOI:10.1002/prac.19943360407

Reference yield:

: 70254-44-3
2,4-dihydroxyquinoline

: 132521-66-5
2,4-dichloro-3-nitroquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: nitric acid / water; acetic acid

2: trichlorophosphate

With nitric acid; trichlorophosphate; In water; acetic acid;