2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-amine

Base Information

Chemical Name:2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-amine
CAS No.:1263077-30-0
Molecular Formula:C₁₅H₂₄BNO₂
Molecular Weight:261.172
Hs Code.:

Synonyms:2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-amine

Suppliers and Price of 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-amine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-amine

Chemical Property:

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Technology Process of 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-amine

There total 1 articles about 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17797-12-5
1-(4-bromophenyl)-1-methylethylamine

: 73183-34-3
bis(pinacol)diborane

: 1263077-30-0
2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-amine

Guidance literature:: With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; at 90 ℃; for 6.5h; Inert atmosphere;

Reference yield: 46.0%

: 1263077-30-0
2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-amine

: tert-butyl ((1R,3R)-7-bromo-1-(2-chloro-6-(trifluoromethoxy)phenyl)-6-fluoro-2,3-dihydro-1H-benzo[d]pyrrolo[1,2-a]imidazole-3-yl)carbamate

: tert-butyl ((1R,3R)-7-(4-(2-aminopropan-2-yl)phenyl)-1-(2-chloro-6-(trifluoromethoxy)-phenyl)-6-fluoro-2,3-dihydro-1H-benzo[d]pyrrolo[1,2-a]imidazole-3-yl)carbamate

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium carbonate; tri tert-butylphosphoniumtetrafluoroborate; In 1,4-dioxane; water; at 90 ℃; for 3h; Inert atmosphere;

Reference yield:

: 1263077-22-0
7-chloro-5-(ethylamino)-3-methylpyrido[4,3-d]pyrimidin-4(3H)-one

: 1263077-30-0
2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-amine

: 7-(4-(2-aminopropan-2-yl)phenyl)-5-(ethylamino)-3-methylpyrido[4,3-d]pyrimidin-4(3H)-one hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane; water / 16 h / 90 °C / Inert atmosphere

2: hydrogenchloride / dichloromethane; water; methanol

With hydrogenchloride; sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; methanol; dichloromethane; water;