4-(4-Chlor-2-nitrophenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester

Base Information

Chemical Name:4-(4-Chlor-2-nitrophenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester
CAS No.:81321-53-1
Molecular Formula:C₁₈H₁₃ClFN₃O₄
Molecular Weight:389.77
Hs Code.:

Synonyms:4-(4-Chlor-2-nitrophenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester

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Chemical Property of 4-(4-Chlor-2-nitrophenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester

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Technology Process of 4-(4-Chlor-2-nitrophenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester

There total 3 articles about 4-(4-Chlor-2-nitrophenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-(4-Chloro-2-nitro-phenyl)-5-dimethylamino-1-(4-fluoro-phenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester

: 81321-53-1
4-(4-Chlor-2-nitrophenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; water; at 100 ℃; for 1h;

Reference yield:

: 89-59-8
4-chloro-2-nitrotoluene

: 81321-53-1
4-(4-Chlor-2-nitrophenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester

Guidance literature:: Multi-step reaction with 3 steps

2: triethylamine / CHCl₃ / 1.) 3 h, reflux; 2.) room temp.

3: HCl / dioxane; H₂O / 1 h / 100 °C

With hydrogenchloride; triethylamine; In 1,4-dioxane; chloroform; water;

Reference yield:

: 32989-56-3
4-chloro-1-[(2-dimethylamino)ethenyl]-2-nitrobenzene

: 81321-53-1
4-(4-Chlor-2-nitrophenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / CHCl₃ / 1.) 3 h, reflux; 2.) room temp.

2: HCl / dioxane; H₂O / 1 h / 100 °C

With hydrogenchloride; triethylamine; In 1,4-dioxane; chloroform; water;