4-(2-Amino-4-chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester

Base Information

Chemical Name:4-(2-Amino-4-chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester
CAS No.:81321-54-2
Molecular Formula:C₁₈H₁₅ClFN₃O₂
Molecular Weight:359.787
Hs Code.:

Synonyms:4-(2-Amino-4-chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester

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Chemical Property of 4-(2-Amino-4-chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester

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Technology Process of 4-(2-Amino-4-chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester

There total 4 articles about 4-(2-Amino-4-chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 81321-53-1
4-(4-Chlor-2-nitrophenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester

: 81321-54-2
4-(2-Amino-4-chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester

Guidance literature:: With hydrogen; nickel; In ethanol; under 73550.8 Torr; Ambient temperature;

Reference yield:

: 89-59-8
4-chloro-2-nitrotoluene

: 81321-54-2
4-(2-Amino-4-chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester

Guidance literature:: Multi-step reaction with 4 steps

2: triethylamine / CHCl₃ / 1.) 3 h, reflux; 2.) room temp.

3: HCl / dioxane; H₂O / 1 h / 100 °C

4: 90 percent / hydrogen / Raney-nickel / ethanol / 73550.8 Torr / Ambient temperature

With hydrogenchloride; hydrogen; triethylamine; nickel; In 1,4-dioxane; ethanol; chloroform; water;

Reference yield:

: 32989-56-3
4-chloro-1-[(2-dimethylamino)ethenyl]-2-nitrobenzene

: 81321-54-2
4-(2-Amino-4-chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / CHCl₃ / 1.) 3 h, reflux; 2.) room temp.

2: HCl / dioxane; H₂O / 1 h / 100 °C

3: 90 percent / hydrogen / Raney-nickel / ethanol / 73550.8 Torr / Ambient temperature

With hydrogenchloride; hydrogen; triethylamine; nickel; In 1,4-dioxane; ethanol; chloroform; water;