2-Bromopropanediamide

Base Information

• Chemical Name: 2-Bromopropanediamide
• CAS No.: 1186-67-0
• Molecular Formula: C3H5 Br N2 O2
• Molecular Weight: 180.989
• Hs Code.: 2924199090
• DSSTox Substance ID: DTXSID30533619
• Wikidata: Q82407014
• Mol file: 1186-67-0.mol

Synonyms:2-BROMOPROPANEDIAMIDE;1186-67-0;Propanediamide,2-bromo-;Propanediamide, 2-bromo-;2-BROMOMALONAMIDE;bromomalonamide;alpha-bromomalonamide;SCHEMBL380421;DTXSID30533619;KDBUUJSOUXNTOE-UHFFFAOYSA-N;AKOS006228686

Chemical Property of 2-Bromopropanediamide

Chemical Property:

• PSA: 86.18000
• LogP: 0.12110
• XLogP3: -0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 179.95344
• Heavy Atom Count: 8
• Complexity: 111

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(=O)N)(C(=O)N)Br

Technology Process of 2-Bromopropanediamide

There total 4 articles about 2-Bromopropanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

malonodiamide (108-13-4) → 2-bromomalonamide (1186-67-0)

Guidance literature:

With bromine; In acetic acid; at 60 ℃; for 5h;

Reference yield:

cyanoacetic acid amide (107-91-5) → 2-bromomalonamide (1186-67-0)

Guidance literature:

With bromine;

DOI:10.1248/cpb.22.965

Reference yield:

malonodiamide (108-13-4) + bromine (7726-95-6) + acetic acid (64-19-7,77671-22-8) → 2-bromomalonamide (1186-67-0)

Guidance literature:

upstream raw materials:

malonodiamide

cyanoacetic acid amide

bromine

acetic acid

Downstream raw materials:

[4-(dicarbamoylmethyl-amino)-phenyl]-arsonic acid

bromine

malonodiamide

2-Benzylamino-malonamide