3-Hydroxy-2,4,6-triiodobenzaldehyde

Base Information

• Chemical Name: 3-Hydroxy-2,4,6-triiodobenzaldehyde
• CAS No.: 224641-82-1
• Molecular Formula: C7H3 I3 O2
• Molecular Weight: 499.813
• NSC Number: 41710
• DSSTox Substance ID: DTXSID20285413
• Wikidata: Q82020774
• Mol file: 224641-82-1.mol

Synonyms:3-hydroxy-2,4,6-triiodobenzaldehyde;NSC41710;224641-82-1;SCHEMBL22897419;DTXSID20285413;NSC-41710

Chemical Property of 3-Hydroxy-2,4,6-triiodobenzaldehyde

Chemical Property:

• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 499.7267
• Heavy Atom Count: 12
• Complexity: 176

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C(=C(C(=C1I)O)I)C=O)I

Technology Process of 3-Hydroxy-2,4,6-triiodobenzaldehyde

There total 3 articles about 3-Hydroxy-2,4,6-triiodobenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

meta-hydroxybenzaldehyde (100-83-4) → 3-hydroxy-2,4,6-triiodobenzaldehyde (224641-82-1)

Guidance literature:

With [bis(pyridine)iodine]⁺ tetrafluoroborate; In dichloromethane; dimethyl sulfoxide;

DOI:10.1016/S0040-4039(99)00348-2

Reference yield:

meta-hydroxybenzaldehyde (100-83-4) → 3-hydroxy-2,6-diiodo-benzaldehyde (683228-53-7) + 3-hydroxy-2,4,6-triiodobenzaldehyde (224641-82-1)

Guidance literature:

With water; iodine; sodium carbonate;

DOI:10.1039/jr9370000076

Reference yield:

water (7732-18-5) + iodine (7553-56-2,12190-71-5,8031-47-8) + sodium acetate (127-09-3) + meta-hydroxybenzaldehyde (100-83-4) → 2-iodo-5-hydroxybenzaldehyde (50765-11-2) + 3-hydroxy-2,6-diiodo-benzaldehyde (683228-53-7) + 3-hydroxy-2,4,6-triiodobenzaldehyde (224641-82-1)

Guidance literature:

DOI:10.1039/jr9370000076

upstream raw materials:

meta-hydroxybenzaldehyde

water

iodine

sodium acetate

Downstream raw materials:

3-hydroxy-4-iodobenzaldehyde

3-hydroxy-2,4,6-trimethylbenzaldehyde