1-(8-Bromo-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b']difuran-4-yl)propan-2-amine

Base Information

Chemical Name:1-(8-Bromo-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b']difuran-4-yl)propan-2-amine
CAS No.:219986-75-1
Molecular Formula:C₁₃H₁₆BrNO₂
Molecular Weight:298.18
Hs Code.:2932190090
UNII:7FBG8DMS2E
DSSTox Substance ID:DTXSID80434288
Nikkaji Number:J748.836J
Wikidata:Q82248650
Pharos Ligand ID:5MMQ44BXYTM2
ChEMBL ID:CHEMBL101008
Mol file:219986-75-1.mol

Synonyms:219986-75-1;1-(8-Bromo-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b']difuran-4-yl)propan-2-amine;3C-B-Fly;2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']difuran-4-yl)-1-methyl-ethylamine;7FBG8DMS2E;1-(4-bromo-2,3,6,7-tetrahydrofuro[2,3-f][1]benzofuran-8-yl)propan-2-amine;CHEMBL101008;2-(8-BROMO-2,3,6,7-TETRAHYDRO-BENZO[1,2-B;1-(8-Bromo-2,3,6,7-tetrahydrobenzo(1,2-b:4,5-b')difuran-4-yl)propan-2-amine;UNII-7FBG8DMS2E;DTXSID80434288;FKRREVSELFOLDT-UHFFFAOYSA-N;BDBM50052337;AKOS015965127;PD047589;FT-0659128;A815817;1-(8-Bromo-2,3,6,7-tetrahydrodibenzo[1,2-b;4,5-b']difuran-4-yl-2-aminopropane;2-(8-bromo-2,3,6,7-tetrahydro-benzo[1,2-b:4,5-b']difuran-4-yl)-1-methyl-ethylamine;2-(8-bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b'']difuran-4-yl)-1-methyl-ethylamine;2-(8-bromo-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b']difuran-4-yl)-1-methylethylamine;8-Bromo-2,3,6,7-tetrahydro-alpha-methyl-benzo(1,2-b:4,5-b')difuran-4-ethanamine;alpha-Methyl-8-bromo-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b']difuran-4-(ethanamine);Benzo(1,2-b:4,5-b')difuran-4-ethanamine, 8-bromo-2,3,6,7-tetrahydro-alpha-methyl-;8-BROMO-2,3,6,7-TETRAHYDRO-.ALPHA.-METHYL-BENZO(1,2-B:4,5-B')DIFURAN-4-ETHANAMINE;BENZO(1,2-B:4,5-B')DIFURAN-4-ETHANAMINE, 8-BROMO-2,3,6,7-TETRAHYDRO-.ALPHA.-METHYL-

Suppliers and Price of 1-(8-Bromo-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b']difuran-4-yl)propan-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(8-Bromo-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b']difuran-4-yl)propan-2-amine 95+%
1g
$ 772.00

American Custom Chemicals Corporation
2-(8-BROMO-2,3,6,7-TETRAHYDRO-BENZO[1,2-B:4,5-B']DIFURAN-4-YL)-1-METHYL-ETHYLAMINE 95.00%
5G
$ 909.56

Total 10 raw suppliers

Chemical Property of 1-(8-Bromo-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b']difuran-4-yl)propan-2-amine

Chemical Property:

Boiling Point:420.622oC at 760 mmHg
Flash Point:208.185oC
PSA：44.48000
Density:1.496g/cm3
LogP:2.90890
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:297.03644
Heavy Atom Count:17
Complexity:289

Purity/Quality:

97% ^*data from raw suppliers

1-(8-Bromo-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b']difuran-4-yl)propan-2-amine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC1=C2CCOC2=C(C3=C1OCC3)Br)N

Technology Process of 1-(8-Bromo-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b']difuran-4-yl)propan-2-amine

There total 14 articles about 1-(8-Bromo-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b']difuran-4-yl)propan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 81926-24-1
4,10-dioxatricyclo[7.3.0.0^3,7]dodeca-1,3⁽⁷⁾,8-triene

: 219986-75-1
(S)-(+)-1-(8-bromo-2,3,6,7-tetrahydrobenzo[1,2-b;4,5-b']difuran-4-yl)-2-aminopropane

Guidance literature:: Multi-step reaction with 4 steps

1: AlCl₃ / CH₂Cl₂ / 16 h

2: 94 percent / TFA; Et₃SiH / 6 h / Heating

3: 82 percent / Br₂ / acetic acid / 4.5 h / 20 °C

4: aq. 5 N NaOH / methanol

With triethylsilane; sodium hydroxide; aluminium trichloride; bromine; trifluoroacetic acid; In methanol; dichloromethane; acetic acid; 1: Friedel-Crafts acylation;
DOI:10.1021/jm000491y

Reference yield:

: 81926-24-1
4,10-dioxatricyclo[7.3.0.0^3,7]dodeca-1,3⁽⁷⁾,8-triene

: 219986-75-1
(R)-(-)-1-(8-bromo-2,3,6,7-tetrahydrobenzo[1,2-b;4,5-b']difuran-4-yl)-2-aminopropane

Guidance literature:: Multi-step reaction with 4 steps

1: AlCl₃ / CH₂Cl₂ / 16 h

2: 92 percent / TFA; Et₃SiH / 6 h / Heating

3: 79 percent / Br₂ / acetic acid / 4.5 h / 20 °C

4: aq. 5 N NaOH / methanol

With triethylsilane; sodium hydroxide; aluminium trichloride; bromine; trifluoroacetic acid; In methanol; dichloromethane; acetic acid; 1: Friedel-Crafts acylation;
DOI:10.1021/jm000491y